4.8 Article

Case 26-2021: A 49-Year-Old Man with Relapsed Acute Myeloid Leukemia

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NEW ENGLAND JOURNAL OF MEDICINE
卷 385, 期 9, 页码 834-843

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MASSACHUSETTS MEDICAL SOC
DOI: 10.1056/NEJMcpc2103458

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The text discusses the evaluation of a 49-year-old man with relapsed acute myeloid leukemia, identifying a new FLT3-ITD mutation through molecular genetic profiling. Management decisions were made based on a bone marrow biopsy.
A Man with Relapsed Acute Myeloid Leukemia A 49-year-old man was evaluated because of relapsed acute myeloid leukemia that occurred 14 months after the initial diagnosis and treatment. Molecular genetic profiling at the time of relapse identified a new internal tandem duplication mutation in FLT3 (FLT3-ITD). A bone marrow biopsy was performed, and management decisions were made.

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