Morbidity and Function Loss After Resection of Malignant Peripheral Nerve Sheath Tumors

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas. Their resection may lead to serious morbidity. Incidence of postoperative motor and sensory deficits is unknown, and reconstruction aimed at restoring such deficits is infrequently carried out. OBJECTIVE: To identify the incidence and risk factors of postoperative morbidity in MPNST as well as the use and outcomes of functional reconstructions in these patients. METHODS: Postoperative function and treatment of MPNSTs diagnosed from 1988 to 2019 in 10 cancer centers was obtained. Two models were constructed evaluating factors independently associated with postoperative motor (

Automated summary

This study aimed to investigate postoperative morbidity and the use and outcomes of functional reconstructions in patients with malignant peripheral nerve sheath tumors (MPNSTs). The results showed that the incidence of postoperative motor and sensory deficits is still unknown, and the use of functional reconstructions is infrequent.