CA2 beyond social memory: Evidence for a fundamental role in hippocampal information processing

Hippocampal region CA2 has received increased attention due to its importance in social recognition memory. While its specific function remains to be identified, there are indications that CA2 plays a major role in a variety of situations, widely extending beyond social memory. In this targeted review, we highlight lines of research which have begun to converge on a more fundamental role for CA2 in hippocampus-dependent memory processing. We discuss recent proposals that speak to the computations CA2 may perform within the hippocampal circuit.

Automated summary

CA2 in the hippocampal region is gaining increased attention for its role in social recognition memory, as well as its broader functions in memory processing. Recent research suggests that CA2 may play a fundamental role in hippocampus-dependent memory processing tasks.