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Max Lam et al.
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Alessandro Vitriolo et al.
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Bingxin Zhao et al.
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Tiffany A. Greenwood et al.
JAMA PSYCHIATRY (2019)
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Emily A. King et al.
PLOS GENETICS (2019)
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Ian J. Deary et al.
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W. David Hill et al.
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Sudeep Pushpakom et al.
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Jeanne E. Savage et al.
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Ashleigh E. Schaffer et al.
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Patrick Turley et al.
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Unexplored therapeutic opportunities in the human genome
Tudor I. Oprea et al.
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Gail Davies et al.
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Ting Qi et al.
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Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
Alvaro N. Barbeira et al.
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Stefano Berto et al.
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Nenad Sestan
SCIENCE (2018)
Comprehensive functional genomic resource and integrative model for the human brain
Daifeng Wang et al.
SCIENCE (2018)
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk
Prashanth Rajarajan et al.
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LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis
Jie Zheng et al.
BIOINFORMATICS (2017)
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J. W. Trampush et al.
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Steven M. Corsello et al.
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Hon-Cheong So et al.
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Bernard Ng et al.
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Chris Finan et al.
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Kyoko Watanabe et al.
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Ake T. Lu et al.
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Max Lam et al.
CELL REPORTS (2017)
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H. A. Gaspar et al.
SCIENTIFIC REPORTS (2017)
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Asma Salimzade et al.
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GWAS for executive function and processing speed suggests involvement of the CADM2 gene
C. A. Ibrahim-Verbaas et al.
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C. Bonvicini et al.
MOLECULAR PSYCHIATRY (2016)
Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112151) and 24 GWAS consortia
S. P. Hagenaars et al.
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Zhihong Zhu et al.
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Tarjinder Singh et al.
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Gerome Breen et al.
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Menachem Fromer et al.
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Jaeseung Kang et al.
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Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions
W. D. Hill et al.
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Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach
Douglas M. Ruderfer et al.
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Genome-wide Studies of Verbal Declarative Memory in Nondemented Older People: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium
Stephanie Debette et al.
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Targeting the schizophrenia genome: a fast track strategy from GWAS to clinic
T. Lencz et al.
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MAGMA: Generalized Gene-Set Analysis of GWAS Data
Christiaan A. de Leeuw et al.
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Synaptic, transcriptional and chromatin genes disrupted in autism
Silvia De Rubeis et al.
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What are lipoproteins doing in the brian?
Hong Wang et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)
Lipoprotein Lipase in the Brain and Nervous System
Hong Wang et al.
ANNUAL REVIEW OF NUTRITION, VOL 32 (2012)
Diagnosing the decline in pharmaceutical R&D efficiency
Jack W. Scannell et al.
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Marco Mula
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Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking
A. Terracciano et al.
TRANSLATIONAL PSYCHIATRY (2011)
Analytical approaches to RNA profiling data for the identification of genes enriched in specific cells
Joseph D. Dougherty et al.
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ZNF536, a Novel Zinc Finger Protein Specifically Expressed in the Brain, Negatively Regulates Neuron Differentiation by Repressing Retinoic Acid-Induced Gene Transcription
Zhen Qin et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Expression of Catenin family members CTNNA1, CTNNA2, CTNNB1 and JUP in the primate prefrontal cortex and hippocampus
A Smith et al.
MOLECULAR BRAIN RESEARCH (2005)
Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network
GH Tai et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
The druggable genome
AL Hopkins et al.
NATURE REVIEWS DRUG DISCOVERY (2002)
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