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Brain sex differences: the androgynous brain is advantageous for mental health and well-being

NEUROPSYCHOPHARMACOLOGY (2022)

The Human Brain Is Best Described as Being on a Female/Male Continuum: Evidence from a Neuroimaging Connectivity Study

Yi Zhang et al.

Summary: This study found that global functional connectivity was stronger in the male brain before middle age but became weaker after that when compared with the female brain. A brain gender continuum was defined based on the likelihood of an observed functional connectivity matrix representing a male brain, with individuals at the center of the continuum showing fewer internalizing symptoms. These findings suggest the existence of a neuroimaging concept of androgyny using the brain gender continuum, which may be associated with better mental health.

CEREBRAL CORTEX (2021)

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Article Neurosciences