相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration
Veronica H. Ryan et al.
EMBO JOURNAL (2021)
HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells
Haiyang Yu et al.
SCIENCE (2021)
LncRNA-dependent nuclear stress bodies promote intron retention through SR protein phosphorylation
Kensuke Ninomiya et al.
EMBO JOURNAL (2020)
The liquid state of FG-nucleoporins mimics permeability barrier properties of nuclear pore complexes
Giorgia Celetti et al.
JOURNAL OF CELL BIOLOGY (2020)
Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS Mutations
Amirhossein Ghanbari Niaki et al.
MOLECULAR CELL (2020)
Distinct Features of Stress Granule Proteins Predict Localization in Membraneless Organelles
Erich R. Kuechler et al.
JOURNAL OF MOLECULAR BIOLOGY (2020)
Solid-State NMR Reveals the Structural Transformation of the TDP-43 Amyloidogenic Region upon Fibrillation
Xiao-Feng Zhuo et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)
Stress granule mediated protein aggregation and underlying gene defects in the FTD-ALS spectrum
Yalda Baradaran-Heravi et al.
NEUROBIOLOGY OF DISEASE (2020)
Widespread remodeling of proteome solubility in response to different protein homeostasis stresses
Xiaojing Sui et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
TDP-43 α-helical structure tunes liquid-liquid phase separation and function
Alexander E. Conicella et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization
David W. Sanders et al.
CELL (2020)
G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules
Peiguo Yang et al.
CELL (2020)
RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation
Jordina Guillen-Boixet et al.
CELL (2020)
Liquid-Liquid Phase Separation and Its Mechanistic Role in Pathological Protein Aggregation
W. Michael Babinchak et al.
JOURNAL OF MOLECULAR BIOLOGY (2020)
Stress Induces Dynamic, Cytotoxicity-Antagonizing TDP-43 Nuclear Bodies via Paraspeckle LncRNA NEAT1-Mediated Liquid-Liquid Phase Separation
Chen Wang et al.
MOLECULAR CELL (2020)
Enzymatic degradation ofRNAcauses widespread protein aggregation in cell and tissue lysates
Johan Aarum et al.
EMBO REPORTS (2020)
Weak binding to the A2RE RNA rigidifies hnRNPA2 RRMs and reduces liquid-liquid phase separation and aggregation
Veronica H. Ryan et al.
NUCLEIC ACIDS RESEARCH (2020)
The molecular language of membraneless organelles
Edward Gomes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
The role of liquid-liquid phase separation in aggregation of the TDP-43 low-complexity domain
W. Michael Babinchak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation
Rachel L. French et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
The proteostasis network and its decline in ageing
Mark S. Hipp et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43
Jacob R. Mann et al.
NEURON (2019)
Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death
Fatima Gasset-Rosa et al.
NEURON (2019)
Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis
Archana Prasad et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)
Aberrant Phase Transitions: Side Effects and Novel Therapeutic Strategies in Human Disease
Veronica Verdile et al.
FRONTIERS IN GENETICS (2019)
Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report
Peter T. Nelson et al.
BRAIN (2019)
Spontaneous driving forces give rise to protein-RNA condensates with coexisting phases and complex material properties
Steven Boeynaems et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
An Intramolecular Salt Bridge Linking TDP43 RNA Binding, Protein Stability, and TDP43-Dependent Neurodegeneration
Brittany N. Flores et al.
CELL REPORTS (2019)
Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD
Mark Y. Fang et al.
NEURON (2019)
The nucleolus functions as a phase-separated protein quality control compartment
F. Frottin et al.
SCIENCE (2019)
RNA structure drives interaction with proteins
Natalia Sanchez de Groot et al.
NATURE COMMUNICATIONS (2019)
Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders
Allison J. Schaser et al.
SCIENTIFIC REPORTS (2019)
Nascent Pre-rRNA Sorting via Phase Separation Drives the Assembly of Dense Fibrillar Components in the Human Nucleolus
Run-Wen Yao et al.
MOLECULAR CELL (2019)
Controlling the material properties and rRNA processing function of the nucleolus using light
Lian Zhu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy
Han-Jou Chen et al.
BRAIN (2019)
Transcriptome-Wide Comparison of Stress Granules and P-Bodies Reveals that Translation Plays a Major Role in RNA Partitioning
Tyler Matheny et al.
MOLECULAR AND CELLULAR BIOLOGY (2019)
Stress granules and neurodegeneration
Benjamin Wolozin et al.
NATURE REVIEWS NEUROSCIENCE (2019)
Expanded polyglutamine impairs normal nuclear distribution of fused in sarcoma and poly (rC)-binding protein 1 in Huntington's disease
Shinichiro Mori et al.
NEUROPATHOLOGY (2019)
Aggregation of the nucleic acid-binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation
Youjun Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity
Fionna E. Loughlin et al.
MOLECULAR CELL (2019)
The physical forces mediating self-association and phase-separation in the C-terminal domain of TDP-43
Hao-Ru Li et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2018)
Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation
Mario Hofweber et al.
CELL (2018)
Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules
Sebastian Markmiller et al.
CELL (2018)
A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
Jie Wang et al.
CELL (2018)
Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains
Lin Guo et al.
CELL (2018)
TAR DNA-binding protein 43 (TDP-43) liquid-liquid phase separation is mediated by just a few aromatic residues
Hao-Ru Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Systematic Characterization of Stress-Induced RNA Granulation
Sim Namkoong et al.
MOLECULAR CELL (2018)
Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation
Veronica H. Ryan et al.
MOLECULAR CELL (2018)
Sequence, Structure, and Context Preferences of Human RNA Binding Proteins
Daniel Dominguez et al.
MOLECULAR CELL (2018)
Functional Domains of NEAT1 Architectural lncRNA Induce Paraspeckle Assembly through Phase Separation
Tomohiro Yamazaki et al.
MOLECULAR CELL (2018)
Mutation analysis of the TIA1 gene in Chinese patients with amyotrophic lateral sclerosis and frontotemporal dementia
Zhenhua Yuan et al.
NEUROBIOLOGY OF AGING (2018)
Structural analyses of NEAT1 IncRNAs suggest long-range RNA interactions that may contribute to paraspeckle architecture
Yizhu Lin et al.
NUCLEIC ACIDS RESEARCH (2018)
RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome
Briana Van Treeck et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
RNA buffers the phase separation behavior of prion-like RNA binding proteins
Shovamayee Maharana et al.
SCIENCE (2018)
mRNA structure determines specificity of a polyQ-driven phase separation
Erin M. Langdon et al.
SCIENCE (2018)
A liquid phase of synapsin and lipid vesicles
Dragomir Milovanovic et al.
SCIENCE (2018)
Phase separation of a yeast prion protein promotes cellular fitness
Titus M. Franzmann et al.
SCIENCE (2018)
Paraspeckles: Where Long Noncoding RNA Meets Phase Separation
Archa H. Fox et al.
TRENDS IN BIOCHEMICAL SCIENCES (2018)
Protein Phase Separation: A New Phase in Cell Biology
Steven Boeynaems et al.
TRENDS IN CELL BIOLOGY (2018)
Self-interaction of NPM1 modulates multiple mechanisms of liquid-liquid phase separation
Diana M. Mitrea et al.
NATURE COMMUNICATIONS (2018)
TIA-1 Self-Multimerization, Phase Separation, and Recruitment into Stress Granules Are Dynamically Regulated by Zn2+
Joseph B. Rayman et al.
CELL REPORTS (2018)
Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization
Ahmed M. Malik et al.
ELIFE (2018)
A New Lens for RNA Localization: Liquid-Liquid Phase Separation
Erin M. Langdon et al.
ANNUAL REVIEW OF MICROBIOLOGY, VOL 72 (2018)
Emerging Roles for Intermolecular RNA-RNA Interactions in RNP Assemblies
Briana Van Treeck et al.
CELL (2018)
Chronic starvation induces noncanonical pro-death stress granules
Lucas C. Reineke et al.
JOURNAL OF CELL SCIENCE (2018)
Who's In and Who's Out-Compositional Control of Biomolecular Condensates
Jonathon A. Ditlev et al.
JOURNAL OF MOLECULAR BIOLOGY (2018)
Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization
Leeanne McGurk et al.
MOLECULAR CELL (2018)
α-Proteobacterial RNA Degradosomes Assemble Liquid-Liquid Phase-Separated RNP Bodies
Nadra Al-Husini et al.
MOLECULAR CELL (2018)
DNA Local-Flexibility-Dependent Assembly of Phase-Separated Liquid Droplets
Anisha Shakya et al.
BIOPHYSICAL JOURNAL (2018)
Simulations of Higher-Order Protein Organizations Using a Fuzzy Framework
B. Tuu-Szabo et al.
COMPLEXITY (2018)
TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle
Thomas O. Vogler et al.
NATURE (2018)
An Integrative Study of Protein-RNA Condensates Identifies Scaffolding RNAs and Reveals Players in Fragile X-Associated Tremor/Ataxia Syndrome
Fernando Cid-Samper et al.
CELL REPORTS (2018)
P-Body Purification Reveals the Condensation of Repressed mRNA Regulons
Arnaud Hubstenberger et al.
MOLECULAR CELL (2017)
The Stress Granule Transcriptome Reveals Principles of mRNA Accumulation in Stress Granules
Anthony Khong et al.
MOLECULAR CELL (2017)
RNA phase transitions in repeat expansion disorders
Ankur Jain et al.
NATURE (2017)
TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics
Ian R. Mackenzie et al.
NEURON (2017)
Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons
Pallavi P. Gopal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Liquid phase condensation in cell physiology and disease
Yongdae Shin et al.
SCIENCE (2017)
ALS/FTD-Associated C9ORF72 Repeat RNA Promotes Phase Transitions In Vitro and in Cells
Marta M. Fay et al.
CELL REPORTS (2017)
RNA stores tau reversibly in complex coacervates
Xuemei Zhang et al.
PLOS BIOLOGY (2017)
Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins
Tyler S. Harmon et al.
ELIFE (2017)
Dysregulation of RNA Binding Protein Aggregation in Neurodegenerative Disorders
Brandon Maziuk et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)
Heterogeneous ribonuclear protein A3 (hnRNP A3) is present in dipeptide repeat protein containing inclusions in Frontotemporal Lobar Degeneration and Motor Neurone disease associated with expansions in C9orf72 gene
Yvonne S. Davidson et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2017)
Clinical and neuropathological features of ALS/FTD with TIA1 mutations
Veronica Hirsch-Reinshagen et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2017)
Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity
Zachary Monahan et al.
EMBO JOURNAL (2017)
Reentrant Phase Transition Drives Dynamic Substructure Formation in Ribonucleoprotein Droplets
Priya R. Banerjee et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
RNA-binding proteins with prion-like domains in health and disease
Alice Ford Harrison et al.
BIOCHEMICAL JOURNAL (2017)
The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis
Han-Jou Chen et al.
BRAIN (2016)
Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity
Menglong Zeng et al.
CELL (2016)
Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism
Shambaditya Saha et al.
CELL (2016)
ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure
Saumya Jain et al.
CELL (2016)
C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
Kyung-Ha Lee et al.
CELL (2016)
Compositional Control of Phase-Separated Cellular Bodies
Salman F. Banani et al.
CELL (2016)
Coexisting Liquid Phases Underlie Nucleolar Subcompartments
Marina Feric et al.
CELL (2016)
Nucleation by rRNA Dictates the Precision of Nucleolus Assembly
Hanieh Falahati et al.
CURRENT BIOLOGY (2016)
Adaptation to stressors by Systemic Protein Amyloidogenesis
Timothy E. Audas et al.
DEVELOPMENTAL CELL (2016)
Protein aggregation and neurodegenerative diseases: From theory to therapy
Vijay Kumar et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
RNA Remodeling Activity of DEAD Box Proteins Tuned by Protein Concentration, RNA Length, and ATP
Younghoon Kim et al.
MOLECULAR CELL (2016)
Membraneless organelles can melt nucleic acid duplexes and act as biomolecular filters
Timothy J. Nott et al.
NATURE CHEMISTRY (2016)
The presence of heterogeneous nuclear ribonucleoproteins in frontotemporal lobar degeneration with FUS-positive inclusions
Priya Gami-Patel et al.
NEUROBIOLOGY OF AGING (2016)
Phase separation of signaling molecules promotes T cell receptor signal transduction
Xiaolei Su et al.
SCIENCE (2016)
ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
Alexander E. Conicella et al.
STRUCTURE (2016)
Principles and Properties of Stress Granules
David S. W. Protter et al.
TRENDS IN CELL BIOLOGY (2016)
In Vivo Formation of Vacuolated Multi-phase Compartments Lacking Membranes
Hermann Broder Schmidt et al.
CELL REPORTS (2016)
Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA
Diana M. Mitrea et al.
ELIFE (2016)
The selective permeability barrier in the nuclear pore complex
Christina Li et al.
NUCLEUS (2016)
The selective permeability barrier in the nuclear pore complex
Christina Li et al.
NUCLEUS (2016)
Defining the spectrum of frontotemporal dementias associated with TARDBP mutations
Paola Caroppo et al.
NEUROLOGY-GENETICS (2016)
The Neuropathology of Chronic Traumatic Encephalopathy
Ann C. McKee et al.
BRAIN PATHOLOGY (2015)
Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress
Edward W. J. Wallace et al.
CELL (2015)
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
Amandine Molliex et al.
CELL (2015)
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
Avinash Patel et al.
CELL (2015)
RNA Controls PolyQ Protein Phase Transitions
Huaiying Zhang et al.
MOLECULAR CELL (2015)
Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
Yuan Lin et al.
MOLECULAR CELL (2015)
Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II
Kathleen A. Burke et al.
MOLECULAR CELL (2015)
ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function
Tetsuro Murakami et al.
NEURON (2015)
RNA transcription modulates phase transition-driven nuclear body assembly
Joel Berry et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics
Shana Elbaum-Garfinkle et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)
Matthias Altmeyer et al.
NATURE COMMUNICATIONS (2015)
Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity
Hermann Broder Schmidt et al.
ELIFE (2015)
RNA Self-Assembly and RNA Nanotechnology
Wade W. Grabow et al.
ACCOUNTS OF CHEMICAL RESEARCH (2014)
Liquid-Liquid Phase Separation in Biology
Anthony A. Hyman et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 30 (2014)
Classification of Intrinsically Disordered Regions and Proteins
Robin van der Lee et al.
CHEMICAL REVIEWS (2014)
Compromised paraspeckle formation as a pathogenic factor in FUSopathies
Tatyana A. Shelkovnikova et al.
HUMAN MOLECULAR GENETICS (2014)
Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations
Nael H. Alami et al.
NEURON (2014)
Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules
Ouissame Bounedjah et al.
NUCLEIC ACIDS RESEARCH (2014)
Casein Kinase II Induced Polymerization of Soluble TDP-43 into Filaments Is Inhibited by Heat Shock Proteins
Yari Carlomagno et al.
PLOS ONE (2014)
hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations
Kohji Mori et al.
ACTA NEUROPATHOLOGICA (2013)
Welander distal myopathy is caused by a mutation in the RNA-binding protein TIA1
Peter Hackman et al.
ANNALS OF NEUROLOGY (2013)
Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm
Tatyana A. Shelkovnikova et al.
CELL CYCLE (2013)
Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes
Aksana A. Labokha et al.
EMBO JOURNAL (2013)
Spliceosome integrity is defective in the motor neuron diseases ALS and SMA
Hitomi Tsuiji et al.
EMBO MOLECULAR MEDICINE (2013)
RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations
J. Gavin Daigle et al.
HUMAN MOLECULAR GENETICS (2013)
The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules
Kyota Yasuda et al.
JOURNAL OF CELL BIOLOGY (2013)
Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics
Desiree M. Baron et al.
MOLECULAR NEURODEGENERATION (2013)
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
Hong Joo Kim et al.
NATURE (2013)
Principles of self-organization in biological pathways: a hypothesis on the autogenous association of alpha-synuclein
Andreas Zanzoni et al.
NUCLEIC ACIDS RESEARCH (2013)
RNA Seeds Higher-Order Assembly of FUS Protein
Jacob C. Schwartz et al.
CELL REPORTS (2013)
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
Oliver D. King et al.
BRAIN RESEARCH (2012)
The Permeability of Reconstituted Nuclear Pores Provides Direct Evidence for the Selective Phase Model
Bastian B. Huelsmann et al.
CELL (2012)
Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
Masato Kato et al.
CELL (2012)
Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies
Tina W. Han et al.
CELL (2012)
Alternative 3′-end processing of long noncoding RNA initiates construction of nuclear paraspeckles
Takao Naganuma et al.
EMBO JOURNAL (2012)
Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis
Julien Couthouis et al.
HUMAN MOLECULAR GENETICS (2012)
Macromolecular Crowding Regulates Assembly of mRNA Stress Granules after Osmotic Stress NEW ROLE FOR COMPATIBLE OSMOLYTES
Ouissame Bounedjah et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Requirements for Stress Granule Recruitment of Fused in Sarcoma (FUS) and TAR DNA-binding Protein of 43 kDa (TDP-43)
Eva Bentmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Contrasting Pathology of the Stress Granule Proteins TIA-1 and G3BP in Tauopathies
Tara Vanderweyde et al.
JOURNAL OF NEUROSCIENCE (2012)
Phase transitions in the assembly of multivalent signalling proteins
Pilong Li et al.
NATURE (2012)
FUS and TDP43 genetic variability in FTD and CBS
Edward D. Huey et al.
NEUROBIOLOGY OF AGING (2012)
Gene Expression Responses to FUS, EWS, and TAF15 Reduction and Stress Granule Sequestration Analyses Identifies FET-Protein Non-Redundant Functions
Jenny Blechingberg et al.
PLOS ONE (2012)
Mutational Analysis Reveals the FUS Homolog TAF15 as a Candidate Gene for Familial Amyotrophic Lateral Sclerosis
N. Ticozzi et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2011)
Single Molecule Study of the Intrinsically Disordered FG-Repeat Nucleoporin 153
Sigrid Milles et al.
BIOPHYSICAL JOURNAL (2011)
FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations
Manuela Neumann et al.
BRAIN (2011)
TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1
Karli K. McDonald et al.
HUMAN MOLECULAR GENETICS (2011)
Accumulation of Transactive Response DNA Binding Protein 43 in Mild Cognitive Impairment and Alzheimer Disease
Cyntia Tremblay et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2011)
Nucleation of nuclear bodies by RNA
Sergey P. Shevtsov et al.
NATURE CELL BIOLOGY (2011)
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
James R. Tollervey et al.
NATURE NEUROSCIENCE (2011)
Nuclear localization sequence of FUS and induction of stress granules by ALS mutants
Jozsef Gal et al.
NEUROBIOLOGY OF AGING (2011)
Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes
Clifford P. Brangwynne et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
A yeast functional screen predicts new candidate ALS disease genes
Julien Couthouis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
Dorothee Dormann et al.
EMBO JOURNAL (2010)
Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules
Daryl A. Bosco et al.
HUMAN MOLECULAR GENETICS (2010)
TDP-43 Proteinopathy and Motor Neuron Disease in Chronic Traumatic Encephalopathy
Ann C. McKee et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2010)
Genetic contribution of FUS to frontotemporal lobar degeneration
T. Van Langenhove et al.
NEUROLOGY (2010)
The RNA-binding protein FUS/TLS is a common aggregate-interacting protein in polyglutamine diseases
Hiroshi Doi et al.
NEUROSCIENCE RESEARCH (2010)
Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue
Liqun Liu-Yesucevitz et al.
PLOS ONE (2010)
Nuclear Stress Bodies
Giuseppe Biamonti et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
A new subtype of frontotemporal lobar degeneration with FUS pathology
Manuela Neumann et al.
BRAIN (2009)
A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins
Simon Alberti et al.
CELL (2009)
FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties
Steffen Frey et al.
EMBO JOURNAL (2009)
Paraspeckles: nuclear bodies built on long noncoding RNA
Charles S. Bond et al.
JOURNAL OF CELL BIOLOGY (2009)
TDP-43 is recruited to stress granules in conditions of oxidative insult
Claudia Colombrita et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Uncoupling Stress Granule Assembly and Translation Initiation Inhibition
Sophie Mokas et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
An Architectural Role for a Nuclear Noncoding RNA: NEAT1 RNA Is Essential for the Structure of Paraspeckles
Christine M. Clemson et al.
MOLECULAR CELL (2009)
Eukaryotic Stress Granules: The Ins and Outs of Translation
J. Ross Buchan et al.
MOLECULAR CELL (2009)
Widespread reorganization of metabolic enzymes into reversible assemblies upon nutrient starvation
Rammohan Narayanaswamy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
Clifford P. Brangwynne et al.
SCIENCE (2009)
Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
Caroline Vance et al.
SCIENCE (2009)
Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
T. J. Kwiatkowski et al.
SCIENCE (2009)
The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response
Mattias K. Andersson et al.
BMC CELL BIOLOGY (2008)
Concomitant TAR-DNA-binding in Alzheimer disease and protein 43 pathology is present corticobasal degeneration but not in other tauopathies
Kunihiro Uryu et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)
TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
Edor Kabashi et al.
NATURE GENETICS (2008)
De Novo Formation of a Subnuclear Body
Trish E. Kaiser et al.
SCIENCE (2008)
Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases
Hanae Nakashima-Yasuda et al.
ACTA NEUROPATHOLOGICA (2007)
A saturated FG-repeat hydrogel can reproduce the permeability properties of nuclear pore complexes
Steffen Frey et al.
CELL (2007)
TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease
Catalina Amador-Ortiz et al.
ANNALS OF NEUROLOGY (2007)
Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex
Samir S. Patel et al.
CELL (2007)
Rapid evolution exposes the boundaries of domain structure and function in natively unfolded FG nucleoporins
Daniel P. Denning et al.
MOLECULAR & CELLULAR PROTEOMICS (2007)
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Tetsuaki Arai et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Manuela Neumann et al.
SCIENCE (2006)
Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2α phosphorylation
Rachid Mazroui et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
hnRNP A1 relocalization to the stress granules reflects a role in the stress response
Sonia Guil et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Processing bodies require RNA for assembly and contain nontranslating mRNAs
D Teixeira et al.
RNA (2005)
A key role for stress-induced satellite III transcripts in the relocalization of splicing factors into nuclear stress granules
A Metz et al.
JOURNAL OF CELL SCIENCE (2004)
Kinesin transports RNA: Isolation and characterization of an RNA-transporting granule
Y Kanai et al.
NEURON (2004)
Protein aggregation and neurodegenerative disease
CA Ross et al.
NATURE MEDICINE (2004)
Stress granule assembly is mediated by prion-like aggregation of TIA-1
N Gilks et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Flavors of protein disorder
S Vucetic et al.
PROTEINS-STRUCTURE FUNCTION AND GENETICS (2003)
Decapping and decay of messenger RNA occur in cytoplasmic processing bodies
U Sheth et al.
SCIENCE (2003)
Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes
SR Kimball et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Functional proteomic analysis of human nucleolus
A Scherl et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
Higher order arrangement of the eukaryotic nuclear bodies
IF Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Heterogeneous nuclear ribonucleoprotein A3, a novel RNA trafficking response element-binding protein
ASW Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Directed proteomic analysis of the human nucleolus
JS Andersen et al.
CURRENT BIOLOGY (2002)
Directed proteomic analysis of the human nucleolus
JS Andersen et al.
CURRENT BIOLOGY (2002)
Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules
N Kedersha et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
Neuronal RNA granules: A link between RNA localization and stimulation-dependent translation
AM Krichevsky et al.
NEURON (2001)
Dynamic shuttling of TIA-1 accompanies the recruitment of mRNA to mammalian stress granules
N Kedersha et al.
JOURNAL OF CELL BIOLOGY (2000)
Nucleated conformational conversion and the replication of conformational information by a prion determinant
TR Serio et al.
SCIENCE (2000)