Strengths and challenges of longitudinal non-human primate neuroimaging

Longitudinal non-human primate neuroimaging has the potential to greatly enhance our understanding of primate brain structure and function. Here we describe its specific strengths, compared to both cross-sectional non-human primate neuroimaging and longitudinal human neuroimaging, but also its associated challenges. We elaborate on factors guiding the use of different analytical tools, subject-specific versus age-specific templates for analyses, and issues related to statistical power.

Automated summary

Longitudinal non-human primate neuroimaging has the potential to enhance our understanding of primate brain structure and function, but also comes with challenges that require the development of more methods and tools to address.