期刊
NATURE REVIEWS MOLECULAR CELL BIOLOGY
卷 23, 期 1, 页码 40-55出版社
NATURE PORTFOLIO
DOI: 10.1038/s41580-021-00407-0
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资金
- European Research Council [695558]
- European Research Council (ERC) [695558] Funding Source: European Research Council (ERC)
This passage discusses the application of machine learning in the analysis of biological data and provides guidance for experimentalists. The increasing scale and complexity of biological data have led to a growing use of machine learning in biology.
Machine learning is becoming a widely used tool for the analysis of biological data. However, for experimentalists, proper use of machine learning methods can be challenging. This Review provides an overview of machine learning techniques and provides guidance on their applications in biology. The expanding scale and inherent complexity of biological data have encouraged a growing use of machine learning in biology to build informative and predictive models of the underlying biological processes. All machine learning techniques fit models to data; however, the specific methods are quite varied and can at first glance seem bewildering. In this Review, we aim to provide readers with a gentle introduction to a few key machine learning techniques, including the most recently developed and widely used techniques involving deep neural networks. We describe how different techniques may be suited to specific types of biological data, and also discuss some best practices and points to consider when one is embarking on experiments involving machine learning. Some emerging directions in machine learning methodology are also discussed.
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