4.8 Article

Towards FAIR nanosafety data

期刊

NATURE NANOTECHNOLOGY
卷 16, 期 6, 页码 644-+

出版社

NATURE PORTFOLIO
DOI: 10.1038/s41565-021-00911-6

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资金

  1. European Union [646221, 814401, 814425]
  2. European Union's 7th Framework Programme project ENPRA (2009-2012) [228789]
  3. European Union's Health Programme Joint Action project NANOGENOTOX (2010-2013) [2009 21 01]
  4. European Union's 7th Framework Programme project NanoTEST (2008-2012) [201335]
  5. European Union's 7th Framework Programme project NANoREG (2013-2017) [310584]
  6. US NIH NCI caNanoLab portal

向作者/读者索取更多资源

The proposal of a FAIR-aligned Nanosafety Data Interface aims to improve findability, accessibility, and interoperability of nanosafety data, providing a path towards standardized and optimized use of existing data to promote safe and sustainable nanotechnology.
The proposal of a FAIR-aligned Nanosafety Data Interface can advance findability, accessibility and interoperability across physicochemical, bio-nano interaction, human toxicity, omics, ecotoxicological and exposure data. Nanotechnology is a key enabling technology with billions of euros in global investment from public funding, which include large collaborative projects that have investigated environmental and health safety aspects of nanomaterials, but the reuse of accumulated data is clearly lagging behind. Here we summarize challenges and provide recommendations for the efficient reuse of nanosafety data, in line with the recently established FAIR (findable, accessible, interoperable and reusable) guiding principles. We describe the FAIR-aligned Nanosafety Data Interface, with an aggregated findability, accessibility and interoperability across physicochemical, bio-nano interaction, human toxicity, omics, ecotoxicological and exposure data. Overall, we illustrate a much-needed path towards standards for the optimized use of existing data, which avoids duplication of efforts, and provides a multitude of options to promote safe and sustainable nanotechnology.

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