4.8 Article

Immunogenicity and safety of the CoronaVac inactivated vaccine in patients with autoimmune rheumatic diseases: a phase 4 trial

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Editorial Material Rheumatology

Anti-SARS-CoV-2 mRNA vaccine in patients with rheumatoid arthritis

Andrea Rubbert-Roth et al.

LANCET RHEUMATOLOGY (2021)

Review Rheumatology

Novel coronavirus disease-2019 (COVID-19) in people with rheumatic disease: Epidemiology and outcomes

Rebecca Grainger et al.

Summary: This review discusses the risk of infection, outcomes, and risk factors for poor outcomes in patients with rheumatic disease in the context of COVID-19. It also explores data from other immune-mediated diseases, limitations of current research efforts, translation of knowledge into practice guidance, and future research agenda.

BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY (2021)

Article Biochemistry & Molecular Biology

Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

Jordan R. Barrett et al.

Summary: The study demonstrates that a booster dose of ChAdOx1 nCoV-19 is safer and better tolerated than priming doses. The booster dose significantly enhances anti-spike neutralizing antibody titers and other functional antibody responses. These data support the two-dose vaccine regime currently being evaluated in phase 3 clinical trials.

NATURE MEDICINE (2021)

Article Multidisciplinary Sciences

Three-quarters attack rate of SARS-CoV-2 in the Brazilian Amazon during a largely unmitigated epidemic

Lewis F. Buss et al.

Summary: Research indicates that the attack rate of COVID-19 in Manaus, the capital of Amazonas state in northern Brazil, reached 66% in June 2020, rising to 76% by October, higher than the estimated attack rate of 29% in Sao Paulo, southeastern Brazil, during the same period.

SCIENCE (2021)

Article Rheumatology

Factors associated with COVID-19-related death in people with rheumatic diseases: results from the COVID-19 Global Rheumatology Alliance physician-reported registry

Anja Strangfeld et al.

Summary: Factors associated with COVID-19-related death in people with rheumatic diseases include age, sex, comorbidities, disease activity, and specific medications. Adequate disease control with disease-modifying anti-rheumatic drugs (DMARDs) without increasing glucocorticoid dosages is important, while caution may be required with certain medications such as rituximab and sulfasalazine.

ANNALS OF THE RHEUMATIC DISEASES (2021)

Article Microbiology

A New SARS-CoV-2 Dual-Purpose Serology Test: Highly Accurate Infection Tracing and Neutralizing Antibody Response Detection

Sean C. Taylor et al.

Summary: The cPass surrogate virus neutralization test (sVNT) is a highly accurate tool for monitoring SARS-CoV-2 immunity, providing valuable assistance in surveillance of infected/recovered and/or vaccinated individuals, as well as in drug and convalescent-phase donor screening. The data also suggest potential applications for calibrating live-cell neutralization tests and longitudinal testing of recovered and/or vaccinated patients.

JOURNAL OF CLINICAL MICROBIOLOGY (2021)

Article Infectious Diseases

Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18-59 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial

Yanjun Zhang et al.

Summary: This study investigated the safety, tolerability, and immunogenicity of the COVID-19 vaccine candidate CoronaVac, and found that the 3 μg dose showed higher seroconversion rates in the phase 2 trial.

LANCET INFECTIOUS DISEASES (2021)

Article Biochemistry & Molecular Biology

Antibody evasion by the P.1 strain of SARS-CoV-2

Wanwisa Dejnirattisai et al.

Summary: Ending the SARS-CoV-2 pandemic requires global vaccination. New virus strains with mutations impact antibody responses, but some variants are less resistant than others. A monoclonal antibody can neutralize different variants and partially restore neutralization potency for other public antibodies.
Article Immunology

Safety of an inactivated SARS-CoV-2 vaccine among healthcare workers in China

Mei-Xian Zhang et al.

Summary: The study aimed to assess the safety of the CoronaVac vaccine among healthcare workers, finding a low incidence of adverse reactions with localized pain at the injection site being the most common, indicating an acceptable safety profile for the vaccine among this population.

EXPERT REVIEW OF VACCINES (2021)

Letter Medicine, General & Internal

Antibody Response to 2-Dose SARS-CoV-2 mRNA Vaccine Series in Solid Organ Transplant Recipients

Brian J. Boyarsky et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

Article Multidisciplinary Sciences

Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil

Nuno R. Faria et al.

Summary: A new variant of concern, P.1, with 17 mutations including three spike protein mutations associated with increased binding to human ACE2 receptors, emerged in Manaus, Brazil between November 2020 and January 2021. Molecular analysis suggests P.1 may be 1.7- to 2.4-fold more transmissible and that previous infection may provide 54 to 79% protection against P.1 infection compared to other lineages. Enhanced global genomic surveillance of such variants is crucial for pandemic response.

SCIENCE (2021)

Editorial Material Medicine, General & Internal

Thrombosis after covid-19 vaccination These rare events must not derail vaccination efforts

Paul R. Hunter

BMJ-BRITISH MEDICAL JOURNAL (2021)

Article Biochemistry & Molecular Biology

Multiplex qPCR discriminates variants of concern to enhance global surveillance of SARS-CoV-2

Chantal B. F. Vogels et al.

Summary: With the emergence of SARS-CoV-2 variants with increased transmissibility and immune escape, targeted surveillance is urgently needed. The B.1.1.7 variant can be detected by a specific deletion in the spike gene, but other variants like B.1.351 and P.1 cannot. An open-source PCR assay targeting a deletion in the ORF1a gene has been designed and validated to enhance surveillance for these variants.

PLOS BIOLOGY (2021)

Article Rheumatology

Antibody response to inactivated COVID-19 vaccine (CoronaVac) in immune-mediated diseases: a controlled study among hospital workers and elderly

Emire Seyahi et al.

Summary: Patients with immune-mediated diseases had lower antibody response to the inactivated COVID-19 vaccine compared to healthy controls, especially those using immunosuppressive or immune-modulating drugs. Older age was also associated with lower antibody titers in both patient and control populations. Further studies are needed to determine if booster doses are necessary for these individuals.

RHEUMATOLOGY INTERNATIONAL (2021)

Article Psychology, Biological

Epidemiological and clinical characteristics of the COVID-19 epidemic in Brazil

William Marciel de Souza et al.

NATURE HUMAN BEHAVIOUR (2020)

Article Multidisciplinary Sciences

Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults

Mark J. Mulligan et al.

NATURE (2020)

Letter Medicine, General & Internal

Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host

Bina Choi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Public, Environmental & Occupational Health

SARS-CoV-2 antibody prevalence in Brazil: results from two successive nationwide serological household surveys

Pedro C. Hallal et al.

LANCET GLOBAL HEALTH (2020)

Article Computer Science, Interdisciplinary Applications

The REDCap consortium: Building an international community of software platform partners

Paul A. Harris et al.

JOURNAL OF BIOMEDICAL INFORMATICS (2019)

Letter Medicine, General & Internal

Prevalence of Immunosuppression Among US Adults, 2013

Rafael Harpaz et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)

Article Rheumatology

A meta-analysis of the risk of venous thromboembolism in inflammatory rheumatic diseases

Jason J. Lee et al.

ARTHRITIS RESEARCH & THERAPY (2014)

Review Immunology

'ASIA' - Autoimmune/inflammatory syndrome induced by adjuvants

Yehuda Shoenfeld et al.

JOURNAL OF AUTOIMMUNITY (2011)

Article Computer Science, Interdisciplinary Applications

Research electronic data capture (REDCap)-A metadata-driven methodology and workflow process for providing translational research informatics support

Paul A. Harris et al.

JOURNAL OF BIOMEDICAL INFORMATICS (2009)