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Luke J. O'Connor et al.
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Luke R. Lloyd-Jones et al.
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Jian Zeng et al.
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Hilary K. Finucane et al.
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Daniel J. Schaid et al.
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Augustine Kong et al.
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Yuval B. Simons et al.
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Amit V. Khera et al.
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Clare Bycroft et al.
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Gleb Kichaev et al.
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Doug Speed et al.
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Cameron Palmer et al.
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Peter M. Visscher et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2017)
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Evan A. Boyle et al.
CELL (2017)
Widespread Allelic Heterogeneity in Complex Traits
Farhad Hormozdiari et al.
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Kevin J. Galinsky et al.
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Huwenbo Shi et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2016)
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Brielin C. Brown et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2016)
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Wenan Chen et al.
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Bjarni J. Vilhjalmsson et al.
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Luigi Palla et al.
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Gleb Kichaev et al.
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David M. Altshuler et al.
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Po-Ru Loh et al.
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Brendan K. Bulik-Sullivan et al.
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Genetically Determined Height and Coronary Artery Disease
C. P. Nelson et al.
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Gerhard Moser et al.
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Advantages and pitfalls in the application of mixed-model association methods
Jian Yang et al.
NATURE GENETICS (2014)
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Or Zuk et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
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Michael C. Turchin et al.
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Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis
Eli A. Stahl et al.
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Hundreds of variants clustered in genomic loci and biological pathways affect human height
Hana Lango Allen et al.
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Jian Yang et al.
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New approaches to population stratification in genome-wide association studies
Alkes L. Price et al.
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Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
Shaun M. Purcell et al.
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Karen N. Conneely et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
A haplotype map of the human genome
D Altshuler et al.
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