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Tracheal remodelling supports stem cells

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NATURE CELL BIOLOGY
卷 23, 期 6, 页码 580-582

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NATURE RESEARCH
DOI: 10.1038/s41556-021-00695-w

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The vascular system is a crucial regulator of adult stem cells, as demonstrated by two studies showing that the vascular-like Drosophila trachea undergoes reshaping after intestinal damage or tumor formation, which is necessary for compensatory intestinal stem cell proliferation and tumor growth.
The vascular system, plastic and positioned in the vicinity of tissues, is an undervalued regulator of adult stem cells. Two studies now show that the vascular-like Drosophila trachea is reshaped after intestinal damage or tumour formation and that this remodelling is required for compensatory intestinal stem cell proliferation and tumour growth.

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