期刊
NATURAL PRODUCT RESEARCH
卷 37, 期 2, 页码 240-247出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2021.1961253
关键词
Entandrophragma angolense; Meliaceae; triterpenoids; cytotoxicity
Two new triterpenoids, entanolide (1) and methyl 3,4-secotirucalla-23-oxo-4(28),7,24-trien-21-al-3-oate (2), were isolated from the bark of Entandrophragma angolense. Compound 2-5 exhibited weak activities in cytotoxicity evaluation against HepG2 cells.
Two new triterpenoids, entanolide (1) and methyl 3,4-secotirucalla-23-oxo-4(28),7,24-trien-21-al-3-oate (2), together with nine known compounds (3-11), were isolated from the bark of Entandrophragma angolense. Their structures were elucidated based on spectroscopic analyses, mainly 1 D and 2 D NMR spectral data. Compounds 1-6 and 8 were evaluated for their cytotoxicity against HepG2 cells, and compounds 2-5 exhibited weak activities.
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