4.4 Review

A comprehensive insight on the biological potential of embelin and its derivatives

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Article Chemistry, Applied

Bioactive benzoquinones content variability in red-berry and white-berry varieties of Ardisia crenata Sims. and assessment of cytotoxic activity

Irma Podolak et al.

Summary: Ardisia crenata has two varieties, with red berries being common and white berries being rare. The roots of the red-berried variety are a valued TCM product containing bioactive benzoquinones. The study found that the white-berried variety has significantly higher levels of rapanone, with this being the first report on rapanone content in various parts of Ardisia crenata and on benzoquinones in the white-berried variety.

NATURAL PRODUCT RESEARCH (2021)

Article Microbiology

In Vitro Analysis of the Antioxidant and Antiviral Activity of Embelin against Herpes Simplex Virus-1

Tony Elias et al.

Summary: Embelin shows noncytotoxicity at tested concentrations and inhibits HSV-1 infection in Vero cells by affecting the early stages of viral attachment and penetration. Additionally, embelin reduces oxidative damage caused by HSV-1 infection, making it an effective antiviral agent in cultured cells. Further research is needed to explore the potential of embelin as a medicinal treatment.

MICROORGANISMS (2021)

Review Chemistry, Medicinal

Synthesis and Biological Activity of Embelin and its Derivatives: An Overview

Zhaojun Sheng et al.

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2020)

Article Biochemistry & Molecular Biology

Embelin averts MPTP-induced dysfunction in mitochondrial bioenergetics and biogenesis via activation of SIRT1

Swetha Pavani Rao et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2020)

Article Plant Sciences

New alkylated benzoquinones from mangrove plant Aegiceras corniculatum with anticancer activity

Yong Li et al.

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2020)

Article Biochemistry & Molecular Biology

Embelin impact on paraquat-induced lung injury through suppressing oxidative stress, inflammatory cascade, and MAPK/NF-κB signaling pathway

Nagaraja SreeHarsha

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2020)

Review Biochemistry & Molecular Biology

Anti-Inflammatory Drugs as Anticancer Agents

Silvia Zappavigna et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Biochemistry & Molecular Biology

Natural Product-Based Nanomedicine in Treatment of Inflammatory Bowel Disease

Tripti Khare et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Biochemistry & Molecular Biology

Efficient Multicomponent Synthesis of Diverse Antibacterial Embelin-Privileged Structure Conjugates

Pedro Martin-Acosta et al.

MOLECULES (2020)

Article Biochemistry & Molecular Biology

Residual Larvicidal Activity of Quinones againstAedes aegypti

Raquel L. Silva et al.

MOLECULES (2020)

Article Integrative & Complementary Medicine

Evaluation of antiplasmodial properties in 15 selected traditional medicinal plants from India

Yogesh Subhash Biradar et al.

JOURNAL OF INTEGRATIVE MEDICINE-JIM (2020)

Review Infectious Diseases

The past, present and future of anti-malarial medicines

Edwin G. Tse et al.

MALARIA JOURNAL (2019)

Review Infectious Diseases

Antimalarial drug resistance in Africa: the calm before the storm?

Melissa D. Conrad et al.

LANCET INFECTIOUS DISEASES (2019)

Review Microbiology

Malaria: The Past and the Present

Jasminka Talapko et al.

MICROORGANISMS (2019)

Article Medicine, General & Internal

Embelin as a Novel Inhibitor of PKC in the Prevention of Platelet Activation and Thrombus Formation

Jiun Yi Li et al.

JOURNAL OF CLINICAL MEDICINE (2019)

Article Pharmacology & Pharmacy

Plant-derived antiviral drugs as novel hepatitis B virus inhibitors: Cell culture and molecular docking study

Mohammad K. Parvez et al.

SAUDI PHARMACEUTICAL JOURNAL (2019)

Article Pharmacology & Pharmacy

Fabrication and evaluation of a medicated hydrogel film with embelin from Embelia ribes for wound healing activity

Hiral Shrimali et al.

FUTURE JOURNAL OF PHARMACEUTICAL SCIENCES (2019)

Article Virology

Antiviral activity of Embelia ribes Burm. f. against influenza virus in vitro

Md Shahadat Hossan et al.

ARCHIVES OF VIROLOGY (2018)

Article Medicine, Research & Experimental

Embelin-loaded oral niosomes ameliorate streptozotocin-induced diabetes in Wistar rats

Md. Shamsir Alam et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Review Chemistry, Medicinal

Embelin: a benzoquinone possesses therapeutic potential for the treatment of human cancer

Kirti S. Prabhu et al.

FUTURE MEDICINAL CHEMISTRY (2018)

Review Biochemistry & Molecular Biology

The Application of Embelin for Cancer Prevention and Therapy

Jeong-Hyeon Ko et al.

MOLECULES (2018)

Article Infectious Diseases

The geography of imported malaria to non-endemic countries: a meta-analysis of nationally reported statistics

Andrew J. Tatem et al.

LANCET INFECTIOUS DISEASES (2017)

Review Biochemistry & Molecular Biology

Chemical and Biological Aspects of the Natural 1,4-Benzoquinone Embelin and its (semi-)Synthetic Derivatives

Priti Singh Shuveksh et al.

CURRENT MEDICINAL CHEMISTRY (2017)

Article Plant Sciences

Domino Synthesis of Embelin Derivatives with Antibacterial Activity

Rosalyn Pena et al.

JOURNAL OF NATURAL PRODUCTS (2016)

Article Biochemistry & Molecular Biology

Embelin Sensitizes Acute Myeloid Leukemia Cells to TRAIL through XIAP Inhibition and NF-κB Inactivation

Tianxin Yang et al.

CELL BIOCHEMISTRY AND BIOPHYSICS (2015)

Article Chemistry, Medicinal

Synthesis and anti-proliferative activities of new derivatives of embelin

Baljinder Singh et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)

Article Biochemistry & Molecular Biology

Probing p300/CBP Associated Factor (PCAF)-Dependent Pathways with a Small Molecule Inhibitor

Rahul Modak et al.

ACS CHEMICAL BIOLOGY (2013)

Article Pharmacology & Pharmacy

Synthesis and Antimicrobial Evaluation of 5-Iodopyrimidine Analogs

N. M. Goudgaon et al.

INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2009)