A comprehensive insight on the biological potential of embelin and its derivatives

Naturally occurring bioactive molecules are known for their diverse biological applications such as antimicrobial, anticancer, anti-inflammatory, and analgesic activities. Also, some of the natural products act as medicinal drugs. Further, bioactive cell-permeable molecule embelin has been reported for its diverse biological activities such as antimalarial, anticancer, and anti-inflammatory in the literature. With the continuation of our research work on biologically active molecules, based on structural activity relationship and docking studies of embelin and its derivatives, we have reported target-specific anticancer and antimalarial activities of embelin and its analogs. Also, it has been reported in many recent research articles that embelin and its derivatives are known to possess medicinal properties. This review mainly highlights recent reports on broad-spectrum biological activities of the embelin and its analogs to date.

Automated summary

This article introduces the diverse biological activities of the naturally occurring bioactive molecule embelin and its derivatives, including anticancer and antimalarial activities. Through structural activity relationship and docking studies, target-specific activities of these molecules have been identified. Recent research indicates that embelin and its derivatives possess a broad spectrum of medicinal properties.