期刊
MOLECULES
卷 26, 期 17, 页码 -出版社
MDPI
DOI: 10.3390/molecules26175238
关键词
fumonisin B1; toxicity; mechanism; contamination; review
资金
- National Natural Science Foundation of China [31872538, 31972746, 31772809]
- Liaoning Provincial Natural Fund Guidance Program Project [2019-ZD-0708]
Fumonisin B1 (FB1) is a highly toxic mycotoxin produced mainly by Fusarium proliferatum and Fusarium verticillioide, causing extensive contamination worldwide in corn, rice, wheat, and their products. It poses health risks and toxicity to animals and humans, inducing oxidative stress, endoplasmic reticulum stress, cellular autophagy, and apoptosis. The review focuses on FB1 contamination, its toxic effects, and potential mechanisms, aiming to provide a reliable reference for understanding FB1 occurrence and toxicity.
Fumonisin B1 (FB1), belonging to the member of fumonisins, is one of the most toxic mycotoxins produced mainly by Fusarium proliferatum and Fusarium verticillioide. FB1 has caused extensive contamination worldwide, mainly in corn, rice, wheat, and their products, while it also poses a health risk and is toxic to animals and human. It has been shown to cause oxidative stress, endoplasmic reticulum stress, cellular autophagy, and apoptosis. This review focuses on the current stage of FB1 contamination, its toxic effects of acute toxicity, immunotoxicity, organ toxicity, and reproductive toxicity on animals and humans. The potential toxic mechanisms of FB1 are discussed. One of the main aims of the work is to provide a reliable reference strategy for understanding the occurrence and toxicity of FB1.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据