期刊
MOLECULES
卷 26, 期 15, 页码 -出版社
MDPI
DOI: 10.3390/molecules26154496
关键词
diaziridines; substituted diaziridines; diazirines; formation; synthesis; transformation; reactivity
资金
- Ministry of Education, Science, Sports and Culture [17K0194007]
This review primarily introduces diaziridine and its importance as a precursor of diazirine photoaffinity probes, discussing recent research trends grouped into three categories and expanding on traditional methods, current research spread, and unconventional synthesis approaches emerging over the past decade.
This review focuses on diaziridine, a high strained three-membered heterocycle with two nitrogen atoms that plays an important role as one of the most important precursors of diazirine photoaffinity probes, as well as their formation and transformation. Recent research trends can be grouped into three categories, based on whether they have examined non-substituted, N-monosubstituted, or N,N-disubstituted diaziridines. The discussion expands on the conventional methods for recent applications, the current spread of studies, and the unconventional synthesis approaches arising over the last decade of publications.
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