Recent Progress Concerning the N-Arylation of Indoles

This review summarizes the current state-of-the-art procedures in terms of the preparation of N-arylindoles. After a short introduction, the transition-metal-free procedures available for the N-arylation of indoles are briefly discussed. Then, the nickel-catalyzed and palladium-catalyzed N-arylation of indoles are both discussed. In the next section, copper-catalyzed procedures for the N-arylation of indoles are described. The final section focuses on recent findings in the field of biologically active N-arylindoles.

Automated summary

This review provides an overview of current state-of-the-art procedures for the preparation of N-arylindoles, including transition-metal-free, nickel-catalyzed, palladium-catalyzed, and copper-catalyzed methods, as well as recent findings in the field of biologically active N-arylindoles.