Congenericity of Claimed Compounds in Patent Applications

A method is presented to analyze quantitatively the degree of congenericity of claimed compounds in patent applications. The approach successfully differentiates patents exemplified with highly congeneric compounds of a structurally compact and well defined chemical series from patents containing a more diverse set of compounds around a more vaguely described patent claim. An application to 750 common patents available in SureChEMBL, SureChEMBLccs and ChEMBL is presented and the congenericity of patent compounds in those different sources discussed.

Automated summary

A method for quantitatively analyzing the congenericity of claimed compounds in patent applications is presented. The method successfully distinguishes patents with highly congeneric compounds from patents with a more diverse set of compounds. The method is applied to 750 common patents from SureChEMBL, SureChEMBLccs, and ChEMBL, and the congenericity of patent compounds in these different sources is discussed.