期刊
MOLECULES
卷 26, 期 11, 页码 -出版社
MDPI
DOI: 10.3390/molecules26113252
关键词
fullerene; anti-tumor; cancer; nanoparticle; nanomedicine
资金
- Science Foundation of Zhejiang Sci-Tech University (ZSTU)
- Zhejiang Provincial Key Laboratory of Silkworm Bioreactor and Biomedicine
The development of novel nanoparticles as a new generation therapeutic drug platform is an active field of chemistry and cancer research. Fullerene nanoparticles have unique physical and chemical properties, excellent biocompatibility, and significant anti-tumor activity. Understanding the anti-tumor mechanism of fullerene nanoparticles is crucial for designing anti-tumor drugs with low toxicity and high targeting.
The development of novel nanoparticles as a new generation therapeutic drug platform is an active field of chemistry and cancer research. In recent years, fullerene nanoparticles have received extensive attention due to their unique physical and chemical properties. Properly modified fullerene nanoparticles have excellent biocompatibility and significant anti-tumor activity, which makes them have broad application prospects in the field of cancer therapy. Therefore, understanding the anti-tumor mechanism of fullerene nanoparticles is of great significance for the design and development of anti-tumor drugs with low toxicity and high targeting. This review has focused on various anti-tumor mechanisms of fullerene derivatives and discusses their toxicity and their distribution in organisms. Finally, the review points out some urgent problems that need solution before fullerene derivatives as a new generation of anti-tumor nano-drug platform enter clinical research.
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