期刊
MOLECULES
卷 26, 期 16, 页码 -出版社
MDPI
DOI: 10.3390/molecules26164722
关键词
COSMOtherm; ready-to-use extracts; grape pomace Grasevina; deep eutectic solvents
资金
- European Union [KK.01.1.1.07.0007]
The aim of this work is to develop an industrially suitable process for the sustainable waste disposal in wine production. The proposed process involves the development of an environmentally friendly method for the isolation of biologically active compounds from Grasevina grape pomace according to the green extraction principles, in order to obtain a ready-to-use extract. Through the use of DES as extraction solvents and the assistance of the COSMOtherm software, the optimal extraction method was successfully screened, ultimately achieving the expected application.
The aim of this work is to develop an industrially suitable process for the sustainable waste disposal in wine production. The proposed process involves the development of an environmentally friendly method for the isolation of biologically active compounds from Grasevina grape pomace according to the green extraction principles, in order to obtain a ready-to-use extract. In this process, deep eutectic solvents (DES) were used as extraction solvents. Aiming to save time in selecting the optimal DES that would provide the most efficient Grasevina pomace polyphenols extraction, the user-friendly software COSMOtherm was used and 45 DES were screened. Moreover, the prepared extracts were chemically and biologically characterized to confirm their safety for human application. Computational and experimental results proved the applicability of COSMOtherm in the selection of the optimal DES for the environmentally friendly preparation of the ready-to-use extract from Grasevina grape pomace with expected application in the cosmetic industry.
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