相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions
Dror Kolodkin-Gal et al.
GUT (2022)
Senolytics for Cancer Therapy: Is All that Glitters Really Gold?
Valerie J. Carpenter et al.
CANCERS (2021)
Expression of therapy-induced senescence markers in breast cancer samples upon incomplete response to neoadjuvant chemotherapy
Tareq Saleh et al.
BIOSCIENCE REPORTS (2021)
Guidelines of care for the management of actinic keratosis
Daniel B. Eisen et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2021)
Ouabain and chloroquine trigger senolysis of BRAF-V600E-induced senescent cells by targeting autophagy
Valentin L'Hote et al.
AGING CELL (2021)
Therapy-Induced Senescence Drives Bone Loss
Zhangting Yao et al.
CANCER RESEARCH (2020)
BH3 mimetics selectively eliminate chemotherapy-induced senescent cells and improve response inTP53wild-type breast cancer
Ashkan Shahbandi et al.
CELL DEATH AND DIFFERENTIATION (2020)
Oncogene-induced senescence: From biology to therapy
Haoran Zhu et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2020)
Therapy-Induced Senescence: An Old Friend Becomes the Enemy
Tareq Saleh et al.
CANCERS (2020)
Navitoclax (ABT263) reduces inflammation and promotes chondrogenic phenotype by clearing senescent osteoarthritic chondrocytes in osteoarthritis
Hao Yang et al.
AGING-US (2020)
Cellular Senescence Promotes Skin Carcinogenesis through p38MAPK and p44/42MAPK Signaling
Fatouma Alimirah et al.
CANCER RESEARCH (2020)
Oncogene-Induced Senescence Limits the Progression of Pancreatic Neoplasia through Production of Activin A
Yajie Zhao et al.
CANCER RESEARCH (2020)
Clearance of senescent cells during cardiac ischemia-reperfusion injury improves recovery
Emily Dookun et al.
AGING CELL (2020)
Clearance of therapy-induced senescent tumor cells by the senolytic ABT-263 via interference with BCL-XL-BAX interaction
Tareq Saleh et al.
MOLECULAR ONCOLOGY (2020)
Morphological changes during replicative senescence in bovine ovarian granulosa cells
Hoang Nghia Son et al.
CELL CYCLE (2019)
Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model
Peisu Zhang et al.
NATURE NEUROSCIENCE (2019)
Acceleration of β Cell Aging Determines Diabetes and Senolysis Improves Disease Outcomes
Cristina Aguayo-Mazzucato et al.
CELL METABOLISM (2019)
Transcriptome signature of cellular senescence
Gabriel Casella et al.
NUCLEIC ACIDS RESEARCH (2019)
Differential expression of senescence tumour markers and its implications on survival outcomes of breast cancer patients
Rahmawati Pare et al.
PLOS ONE (2019)
Controlled induction and targeted elimination of p16INK4a-expressing chondrocytes in cartilage explant culture
Garrett A. Sessions et al.
FASEB JOURNAL (2019)
Cellular Senescence: Defining a Path Forward
Vassilis Gorgoulis et al.
CELL (2019)
Tumor cell escape from therapy-induced senescence
Tareq Saleh et al.
BIOCHEMICAL PHARMACOLOGY (2019)
The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma
Juliane L. Buhl et al.
CLINICAL CANCER RESEARCH (2019)
Roles of Telomere Biology in Cell Senescence, Replicative and Chronological Ageing
Jun Liu et al.
CELLS (2019)
Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction
Anna Walaszczyk et al.
AGING CELL (2019)
Cardiac glycosides are broad-spectrum senolytics
Ana Guerrero et al.
NATURE METABOLISM (2019)
Unmasking senescence: context-dependent effects of SASP in cancer
Douglas V. Faget et al.
NATURE REVIEWS CANCER (2019)
Senescence-associated reprogramming promotes cancer stemness
Maja Milanovic et al.
NATURE (2018)
Oncogene-induced senescence and tumour control in complex biological systems
Lorenzo Galluzzi et al.
CELL DEATH AND DIFFERENTIATION (2018)
Management of cervical premalignant lesions
Partha Basu et al.
CURRENT PROBLEMS IN CANCER (2018)
High-grade prostatic intraepithelial neoplasia, PIN-like carcinoma, ductal carcinoma, and intraductal carcinoma of the prostate
Ming Zhou
MODERN PATHOLOGY (2018)
Hallmarks of Cellular Senescence
Alejandra Hernandez-Segura et al.
TRENDS IN CELL BIOLOGY (2018)
Tau protein aggregation is associated with cellular senescence in the brain
Nicolas Musi et al.
AGING CELL (2018)
Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline
Tyler J. Bussian et al.
NATURE (2018)
The murine dialysis fistula model exhibits a senescence phenotype: pathobiological mechanisms and therapeutic potential
Karl A. Nath et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2018)
Establishment and application of a novel patient-derived KIAA1549: BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing
Florian Selt et al.
ONCOTARGET (2017)
The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration
Birgit Ritschka et al.
GENES & DEVELOPMENT (2017)
Inhibition of Bcl-2/xl With ABT-263 Selectively Kills Senescent Type II Pneumocytes and Reverses Persistent Pulmonary Fibrosis Induced by Ionizing Radiation in Mice
Jin Pan et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2017)
Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma
Jose Mario Gonzalez-Meljem et al.
NATURE COMMUNICATIONS (2017)
Cellular senescence drives age-dependent hepatic steatosis
Mikolaj Ogrodnik et al.
NATURE COMMUNICATIONS (2017)
Tumor cell senescence response produces aggressive variants
Leixiang Yang et al.
CELL DEATH DISCOVERY (2017)
DNA damage and senescence in osteoprogenitors expressing Qsx1 may cause their decrease with age
Ha-Neui Kim et al.
AGING CELL (2017)
Senescence-associated IL-6 and IL-8 cytokines induce a self- and cross-reinforced senescence/inflammatory milieu strengthening tumorigenic capabilities in the MCF-7 breast cancer cell line
Paola Ortiz-Montero et al.
CELL COMMUNICATION AND SIGNALING (2017)
p53 Restoration in Induction and Maintenance of Senescence: Differential Effects in Premalignant and Malignant Tumor Cells
Mohamad Harajly et al.
MOLECULAR AND CELLULAR BIOLOGY (2016)
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
Jianhui Chang et al.
NATURE MEDICINE (2016)
Discovery of piperlongumine as a potential novel lead for the development of senolytic agents
Yingying Wang et al.
AGING-US (2016)
Is Senescence Reversible?
Shweta Chakradeo et al.
CURRENT DRUG TARGETS (2016)
The Achilles' heel of senescent cells: from transcriptome to senolytic drugs
Yi Zhu et al.
AGING CELL (2015)
Senescence as a general cellular response to stress: A mini-review
Irina Fridlyanskaya et al.
EXPERIMENTAL GERONTOLOGY (2015)
Forging a signature of in vivo senescence
Norman E. Sharpless et al.
NATURE REVIEWS CANCER (2015)
The utility of re-excising mildly and moderately dysplastic nevi: A retrospective analysis
Lauren Strazzula et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2014)
Polyploidy road to therapy-induced cellular senescence and escape
Qin Wang et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
Thrombospondin-1 mediates oncogenic Ras-induced senescence in premalignant lung tumors
Kwan-Hyuck Baek et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence
Joanna Kaplon et al.
NATURE (2013)
Absence of Distinguishing Senescence Traits in Human Melanocytic Nevi
Sieu L. Tran et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2012)
Excisional biopsy for management of lateral tongue leukoplakia
Woo-Jin Jeong et al.
JOURNAL OF ORAL PATHOLOGY & MEDICINE (2012)
Cyclin D1 overexpression supports stable EBV infection in nasopharyngeal epithelial cells
Chi Man Tsang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Differences in the expression of five senescence markers in oral cancer, oral leukoplakia and control samples in humans
Antonio Bascones-Martinez et al.
ONCOLOGY LETTERS (2012)
Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner, and follow expression of p16ink4a
Martin Kosar et al.
CELL CYCLE (2011)
Deletion of Rb Accelerates Pancreatic Carcinogenesis by Oncogenic Kras and Impairs Senescence in Premalignant Lesions
Catherine Carriere et al.
GASTROENTEROLOGY (2011)
Senescence in intraductal papillary mucinous neoplasm of the pancreas
Yoshihiro Miyasaka et al.
HUMAN PATHOLOGY (2011)
Escape from p21-mediated Oncogene-induced Senescence Leads to Cell Dedifferentiation and Dependence on Anti-apoptotic Bcl-xL and MCL1 Proteins
Sophie de Carne Trecesson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion
Francis Rodier et al.
JOURNAL OF CELL SCIENCE (2011)
Up and downregulation of p16Ink4a expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancer
Lydia Kriegl et al.
MODERN PATHOLOGY (2011)
Protein modification and replicative senescence of WI-38 human embryonic fibroblasts
Emad K. Ahmed et al.
AGING CELL (2010)
Ductal carcinoma in situ (DCIS): pathological features, differential diagnosis, prognostic factors and specimen evaluation
Sarah E. Pinder
MODERN PATHOLOGY (2010)
Benign and Premalignant Skin Lesions
Erica H. Lee et al.
PLASTIC AND RECONSTRUCTIVE SURGERY (2010)
Activation of fibroblast growth factor receptor 3 and oncogene-induced senescence in skin tumours
Y. Hida et al.
BRITISH JOURNAL OF DERMATOLOGY (2009)
Senescent Stromal-Derived Osteopontin Promotes Preneoplastic Cell Growth
Ermira Pazolli et al.
CANCER RESEARCH (2009)
Cancer stem cells and escape from drug-induced premature senescence in human lung tumor cells Implications for drug resistance and in vitro drug screening models
Michal Sabisz et al.
CELL CYCLE (2009)
A prostatic intraepithelial neoplasia-dependent p27Kip1 checkpoint induces senescence and inhibits cell proliferation and cancer progression
Pradip K. Majumder et al.
CANCER CELL (2008)
Critical pathways in cellular senescence and immortalization revealed by gene expression profiling
A. L. Fridman et al.
ONCOGENE (2008)
Retinoblastoma Loss Modulates DNA Damage Response Favoring Tumor Progression
Marcos Seoane et al.
PLOS ONE (2008)
Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
Jean-Philippe Coppe et al.
PLOS BIOLOGY (2008)
β-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo
Mai Xu et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation
Chi-Hwa Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis
Christopher J. Sarkisian et al.
NATURE CELL BIOLOGY (2007)
Significance of liquefaction degeneration in oral lichen planus: a study of its relationship with apoptosis and cell cycle arrest markers
C. Bascones-Ilundain et al.
CLINICAL AND EXPERIMENTAL DERMATOLOGY (2007)
Dysregulated expression of stem cell factor Bmi1 in precancerous lesions of the gastrointestinal tract
Keisuke Tateishi et al.
CLINICAL CANCER RESEARCH (2006)
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
Jirina Bartkova et al.
NATURE (2006)
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
Raffaella Di Micco et al.
NATURE (2006)
Oncogene-induced cell senescence - Halting on the road to cancer
W. J. Mooi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Cellular senescence in naevi and immortalisation in melanoma: a role for p16?
V. C. Gray-Schopfer et al.
BRITISH JOURNAL OF CANCER (2006)
Oncogene-induced senescence as an initial barrier in lymphoma development
M Braig et al.
NATURE (2005)
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
ZB Chen et al.
NATURE (2005)
BRAFE600-associated senescence-like cell cycle arrest of human naevi
C Michaloglou et al.
NATURE (2005)
Human cell senescence as a DNA damage response
T von Zglinicki et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2005)
P27 and Mib1 expression in actinic keratosis, Bowen disease, and squamous cell carcinoma
CW Oh et al.
AMERICAN JOURNAL OF DERMATOPATHOLOGY (2004)
Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway
H Miyauchi et al.
EMBO JOURNAL (2004)
Morphological adjustment of senescent cells by modulating caveolin-1 status
KA Cho et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Ha-RasG12V induces senescence in primary and immortalized human esophageal keratinocytes with p53 dysfunction
M Takaoka et al.
ONCOGENE (2004)
Molecular signature of oncogenic ras-induced senescence
DX Mason et al.
ONCOGENE (2004)
A DNA damage checkpoint response in telomere-initiated senescence
FD di Fagagna et al.
NATURE (2003)
Reversal of human cellular senescence:: roles of the p53 and p16 pathways
CM Beauséjour et al.
EMBO JOURNAL (2003)
Co-expression of p16INK4A and laminin 5 γ2 by microinvasive and superficial squamous cell carcinomas in vivo and by migrating wound and senescent keratinocytes in culture
E Natarajan et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Reversal of senescence in mouse fibroblasts through lentiviral in suppression of p53
AMG Dirac et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Senescence induced by altered telomere state, not telomere loss
J Karlseder et al.
SCIENCE (2002)
Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence
SG Rane et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Cellular response to oncogenic Ras involves induction of the Cdk4 and Cdk6 inhibitor p15INK4b
M Malumbres et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)