相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Pharmaceutical protein solids: Drying technology, solid-state characterization and stability
Yuan Chen et al.
ADVANCED DRUG DELIVERY REVIEWS (2021)
Effects of drying method and excipient on the structure and physical stability of protein solids: Freeze drying vs. spray freeze drying
Tarun Tejasvi Mutukuri et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)
Probing Microenvironmental Acidity in Lyophilized Protein and Vaccine Formulations Using Solid-state NMR Spectroscopy
Mingyue Li et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2021)
Solid-state NMR spectroscopy in pharmaceutical sciences
Mingyue Li et al.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2021)
Particle engineered mannitol for carrier-based inhalation - A serious alternative?
Nancy Hertel et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)
Surface Composition and Formulation Heterogeneity of Protein Solids Produced by Spray Drying
Nathan E. Wilson et al.
PHARMACEUTICAL RESEARCH (2020)
Quantifying Molecular Mixing and Heterogeneity in Pharmaceutical Dispersions at Sub-100 nm Resolution by Spin Diffusion NMR
Pu Duan et al.
MOLECULAR PHARMACEUTICS (2020)
Molecular Interactions in Posaconazole Amorphous Solid Dispersions from Two-Dimensional Solid-State NMR Spectroscopy
Xingyu Lu et al.
MOLECULAR PHARMACEUTICS (2019)
Effect of thermal and shear stresses in the spray drying process on the stability of siRNA dry powders
Jingya Wu et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)
Effects of drying method and excipient on structure and stability of protein solids using solid-state hydrogen/deuterium exchange mass spectrometry (ssHDX-MS)
Nathan E. Wilson et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)
Effect of Particle Formation Process on Characteristics and Aerosol Performance of Respirable Protein Powders
Ashlee D. Brunaugh et al.
MOLECULAR PHARMACEUTICS (2019)
The use of hydrophobic amino acids in protecting spray dried trehalose formulations against moisture-induced changes
Pei T. Mah et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2019)
Influence of Formulation Factors on the Aerosol Performance and Stability of Lysozyme Powders: a Systematic Approach
Silvia Ferrati et al.
AAPS PHARMSCITECH (2018)
Predicting physical stability of ternary amorphous solid dispersions using specific mechanical energy in a hot melt extrusion process
Masataka Hanada et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)
Improved Physical Stability and Aerosolization of Inhalable Amorphous Ciprofloxacin Powder Formulations by Incorporating Synergistic Colistin
Nivedita Shetty et al.
MOLECULAR PHARMACEUTICS (2018)
Effects of Drying Process on an IgG1 Monoclonal Antibody Using Solid-State Hydrogen Deuterium Exchange with Mass Spectrometric Analysis (ssHDX-MS)
Ehab M. Moussa et al.
PHARMACEUTICAL RESEARCH (2018)
Physico-Chemical Properties, Aerosolization and Dissolution of Co-Spray Dried Azithromycin Particles with L-Leucine for Inhalation
Sharad Mangal et al.
PHARMACEUTICAL RESEARCH (2018)
Protection of hydrophobic amino acids against moisture-induced deterioration in the aerosolization performance of highly hygroscopic spray-dried powders
Jiaqi Yu et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2017)
How sugars protect proteins in the solid state and during drying (review): Mechanisms of stabilization in relation to stress conditions
Maarten A. Mensink et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2017)
Inhaled powder formulation of naked siRNA using spray drying technology with L-leucine as dispersion enhancer
Michael Y. T. Chow et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)
Insights into Nano- and Micron-Scale Phase Separation in Amorphous Solid Dispersions Using Fluorescence-Based Techniques in Combination with Solid State Nuclear Magnetic Resonance Spectroscopy
Hitesh S. Purohit et al.
PHARMACEUTICAL RESEARCH (2017)
Influence of Miscibility of Protein-Sugar Lyophilizates on Their Storage Stability
Maarten A. Mensink et al.
AAPS JOURNAL (2016)
L-Leucine as an excipient against moisture on in vitro aerosolization performances of highly hygroscopic spray-dried powders
Liang Li et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2016)
Magic Angle Spinning NMR of Proteins: High-Frequency Dynamic Nuclear Polarization and H-1 Detection
Yongchao Su et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84 (2015)
Size and Molecular Flexibility of Sugars Determine the Storage Stability of Freeze-Dried Proteins
W. F. Tonnis et al.
MOLECULAR PHARMACEUTICS (2015)
Structural and Dynamic Properties of Amorphous Solid Dispersions: The Role of Solid-State Nuclear Magnetic Resonance Spectroscopy and Relaxometry
Amrit Paudel et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2014)
Investigating Miscibility and Molecular Mobility of Nifedipine-PVP Amorphous Solid Dispersions Using Solid-State NMR Spectroscopy
Xiaoda Yuan et al.
MOLECULAR PHARMACEUTICS (2014)
Predicting Protein Aggregation during Storage in Lyophilized Solids Using Solid State Amide Hydrogen/Deuterium Exchange with Mass Spectrometric Analysis (ssHDX-MS)
Balakrishnan S. Moorthy et al.
MOLECULAR PHARMACEUTICS (2014)
Trehalose limits BSA aggregation in spray-dried formulations at high temperatures: Implications in preparing polymer implants for long-term protein delivery
Karthikan Rajagopal et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2013)
Dry powder inhalers of gentamicin and leucine: formulation parameters, aerosol performance and in vitro toxicity on CuFi1 cells
R. P. Aquino et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2012)
Localized Hydration in Lyophilized Myoglobin by Hydrogen-Deuterium Exchange Mass Spectrometry. 2. Exchange Kinetics
Andreas M. Sophocleous et al.
MOLECULAR PHARMACEUTICS (2012)
NIH Image to ImageJ: 25 years of image analysis
Caroline A. Schneider et al.
NATURE METHODS (2012)
Conformational Disorder of Membrane Peptides Investigated from Solid-State NMR Line Widths and Line Shapes
Yongchao Su et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2011)
Structure and dynamics of cationic membrane peptides and proteins: Insights from solid-state NMR
Mei Hong et al.
PROTEIN SCIENCE (2011)
Spray Drying Technique. I: Hardware and Process Parameters
Krzysztof Cal et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2010)
Mechanisms of Protein Stabilization in the Solid State
Liuquan (Lucy) Chang et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2009)
Effect of particle size of dry powder mannitol on the lung deposition in healthy volunteers
William Glover et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2008)
Development of stable influenza vaccine powder formulations: Challenges and possibilities
J-P. Amorij et al.
PHARMACEUTICAL RESEARCH (2008)
Inhaling medicines: delivering drugs to the body through the lungs
John S. Patton et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
Particle engineering techniques for inhaled biopharmaceuticals
Sunday A. Shoyele et al.
ADVANCED DRUG DELIVERY REVIEWS (2006)
Glass transition temperature of glucose, sucrose, and trehalose: An experimental and in silico study
Alexandra Simperler et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2006)
Differences in the physical state and thermal behavior of spray-dried and freeze-dried lactose and lactose/protein mixtures
Md. Kamrul Haque et al.
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES (2006)
Spray drying of biopharmaceuticals: Stability and process considerations
Mahmoud Ameri et al.
DRYING TECHNOLOGY (2006)
Influence of the active pharmaceutical ingredient concentration on the physical state of mannitol-implications in freeze-drying
XM Liao et al.
PHARMACEUTICAL RESEARCH (2005)
Effect of amino acids on the dispersion of disodium cromoglycate powders
NYK Chew et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2005)
Protein drug stability: A formulation challenge
S Frokjaer et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Effects of annealing lyophilized and spray-lyophilized formulations of recombinant human interferon-γ
SD Webb et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2003)
Different molecular motions in lyophilized protein formulations as determined by laboratory and rotating frame spin-lattice relaxation times
S Yoshioka et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2002)
A solid-state NMR study of protein mobility in lyophilized protein-sugar powders
YH Lam et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2002)
A novel approach to the pulmonary delivery of liposomes in dry powder form to eliminate the deleterious effects of milling
TR Desai et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2002)