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PROGRESS IN NEUROBIOLOGY (2007)
ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease
Hoon Ryu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Mutant huntingtin expression induces mitochondrial calcium handling defects in clonal striatal cells - Functional consequences
Tamara Milakovic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Mitochondrial-dependent Ca2+ handling in Huntington's disease striatal cells:: Effect of histone deacetylase inhibitors
Jorge M. A. Oliveira et al.
JOURNAL OF NEUROSCIENCE (2006)
Cytotoxicity of a mutant huntingtin fragment in yeast involves early alterations in mitochondrial OXPHOS complexes II and III
Asun Solans et al.
HUMAN MOLECULAR GENETICS (2006)
Transcriptional repression of PGC-α by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
Libin Cui et al.
CELL (2006)
Dynasore, a cell-permeable inhibitor of dynamin
Eric Macia et al.
DEVELOPMENTAL CELL (2006)
Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons
DTW Chang et al.
NEUROBIOLOGY OF DISEASE (2006)
Suppression of polyglutamine-induced toxicity in cell and animal models of Huntington's disease by ubiquilin
H Wang et al.
HUMAN MOLECULAR GENETICS (2006)
Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease
A Pal et al.
JOURNAL OF CELL BIOLOGY (2006)
Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond
SA Lipton
NATURE REVIEWS DRUG DISCOVERY (2006)
Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain
S Ginés et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2006)
Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2′dG
SM Hersch et al.
NEUROLOGY (2006)
The chemical biology of clinically tolerated NMDA receptor antagonists
Huei-Sheng Vincent Chen et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's disease
CL Benn et al.
HUMAN MOLECULAR GENETICS (2005)
HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism
IS Seong et al.
HUMAN MOLECULAR GENETICS (2005)
History of genetic disease - The molecular genetics of Huntington disease - a history
GP Bates
NATURE REVIEWS GENETICS (2005)
p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease
BI Bae et al.
NEURON (2005)
Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease
TS Tang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Potentiation of NMDA receptor-mediated excitotoxicity linked with intrinsic apoptotic pathway in YAC transgenic mouse model of Huntington's disease
MM Zeron et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2004)
Huntingtin-protein interactions and the pathogenesis of Huntington's disease|
SH Li et al.
TRENDS IN GENETICS (2004)
Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro
E Trushina et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins
K Huang et al.
NEURON (2004)
Americo Negrette (1924 to 2003) - Diagnosing Huntington disease in Venezuela
MS Okun et al.
NEUROLOGY (2004)
Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release
YS Choo et al.
HUMAN MOLECULAR GENETICS (2004)
Genetic mouse models of Huntington's and Parkinson's diseases: illuminating but imperfect
MS Levine et al.
TRENDS IN NEUROSCIENCES (2004)
Circulating and cerebrospinal fluid ghrelin and leptin: potential role in altered body weight in Huntington's disease
V Popovic et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2004)
Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats
LB Menalled et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2003)
Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease
X Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
C Zuccato et al.
NATURE GENETICS (2003)
Nuclease-deficient FEN-1 blocks rad51/BRCA1-mediated repair and causes trinucleotide repeat instability
C Spiro et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Abnormal association of mutant huntingtin with synaptic vesicles inhibits glutamate release
H Li et al.
HUMAN MOLECULAR GENETICS (2003)
Huntingtin and Huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1
TS Tang et al.
NEURON (2003)
Overexpression and nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase in a transgenic mouse model of Huntington's disease
VV Senatorov et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2003)
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines
AV Panov et al.
NATURE NEUROSCIENCE (2002)
Lessons from animal models of Huntington's disease
DC Rubinsztein
TRENDS IN GENETICS (2002)
Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease
MM Zeron et al.
NEURON (2002)
Mouse models of Huntington's disease
LB Menalled et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2002)
Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease
MB Bogdanov et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice
GJ Klapstein et al.
JOURNAL OF NEUROPHYSIOLOGY (2001)
NMDA receptor function in mouse models of Huntington disease
C Cepeda et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2001)
Expression of the Huntington's disease transgene in neural stem cell cultures from R6/2 transgenic mice
Q Chu-LaGraff et al.
BRAIN RESEARCH BULLETIN (2001)
Polyglutamine-expanded Huntingtin promotes sensitization of N-methyl-D-aspartate receptors via post-synaptic density 95
Y Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Comparative analysis of superoxide dismutase activity between acute pharmacological models and a transgenic mouse model of Huntington's disease
A Santamaría et al.
NEUROCHEMICAL RESEARCH (2001)
Trinucleotide expansion in haploid germ cells by gap repair
IV Kovtun et al.
NATURE GENETICS (2001)
Progression of symptoms in the early and middle stages of Huntington disease
SC Kirkwood et al.
ARCHIVES OF NEUROLOGY (2001)
Dominant phenotypes produced by the HD mutation in STHdhQ111 striatal cells
F Trettel et al.
HUMAN MOLECULAR GENETICS (2000)
Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy
KB Kegel et al.
JOURNAL OF NEUROSCIENCE (2000)
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
JS Steffan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Wild-type Huntingtin protects from apoptosis upstream of caspase-3
D Rigamonti et al.
JOURNAL OF NEUROSCIENCE (2000)
Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease
A Yamamoto et al.
CELL (2000)
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