相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The Influence of Met Receptor Level on HGF-Induced Glycolytic Reprogramming in Head and Neck Squamous Cell Carcinoma
Verena Boschert et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Metabolic Symbiosis in Chemoresistance: Refocusing the Role of Aerobic Glycolysis
Lisi Ma et al.
FRONTIERS IN ONCOLOGY (2020)
Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells
Garry L. Coles et al.
CANCER CELL (2020)
Small Cell Lung Cancer from Traditional to Innovative Therapeutics: Building a Comprehensive Network to Optimize Clinical and Translational Research
Shanmuga Subbiah et al.
JOURNAL OF CLINICAL MEDICINE (2020)
Physiologic functions of PP2A: Lessons from genetically modified mice
Sara Reynhout et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2019)
Targeting-PP2A-in-cancer: Combination therapies
Sahar Mazhar et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2019)
The Antitumor Drug LB-100 Is a Catalytic Inhibitor of Protein Phosphatase 2A (PPP2CA) and 5 (PPP5C) Coordinating with the Active-Site Catalytic Metals in PPP5C
Brandon M. D'Arcy et al.
MOLECULAR CANCER THERAPEUTICS (2019)
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer
Nan Jin et al.
NATURE COMMUNICATIONS (2019)
MET Inhibitors in Small Cell Lung Cancer: From the Bench to the Bedside
Max Hardy-Werbin et al.
CANCERS (2019)
EGFL9 promotes breast cancer metastasis by inducing cMET activation and metabolic reprogramming
Fanyan Meng et al.
NATURE COMMUNICATIONS (2019)
B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies
Gang Xiao et al.
CELL (2018)
Non-genomic mechanisms of protein phosphatase 2A (PP2A) regulation in cancer
Otto Kauko et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2018)
Pharmacologic inhibition of protein phosphatase-2A achieves durable immune-mediated antitumor activity when combined with PD-1 blockade
Winson S. Ho et al.
NATURE COMMUNICATIONS (2018)
Protein Phosphatase 2A in the Regulation of Wnt Signaling, Stem Cells, and Cancer
Joshua J. Thompson et al.
GENES (2018)
Elucidating the Metabolic Plasticity of Cancer: Mitochondrial Reprogramming and Hybrid Metabolic States
Dongya Jia et al.
CELLS (2018)
Reviving oncogenic addiction to MET bypassed by BRAF (G469A) mutation
Anna Rita Virzi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Inhibiting crosstalk between MET signaling and mitochondrial dynamics and morphology: a novel therapeutic approach for lung cancer and mesothelioma
Jiale Wang et al.
CANCER BIOLOGY & THERAPY (2018)
Inhibition of Protein Phosphatase 2A Sensitizes Mucoepidermoid Carcinoma to Chemotherapy via the PI3K-AKT Pathway in Response to Insulin Stimulus
Limin Liu et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
Safety, Tolerability, and Preliminary Activity of LB-100, an Inhibitor of Protein Phosphatase 2A, in Patients with Relapsed Solid Tumors: An Open-Label, Dose Escalation, First-in-Human, Phase I Trial
Vincent Chung et al.
CLINICAL CANCER RESEARCH (2017)
PP2A inhibition from LB100 therapy enhances daunorubicin cytotoxicity in secondary acute myeloid leukemia via miR-181b-1 upregulation
Chao Hu et al.
SCIENTIFIC REPORTS (2017)
QuPath: Open source software for digital pathology image analysis
Peter Bankhead et al.
SCIENTIFIC REPORTS (2017)
Modeling the Genetic Regulation of Cancer Metabolism: Interplay between Glycolysis and Oxidative Phosphorylation
Linglin Yu et al.
CANCER RESEARCH (2017)
PP2A inhibition with LB100 enhances cisplatin cytotoxicity and overcomes cisplatin resistance in medulloblastoma cells
Winson S. Ho et al.
ONCOTARGET (2016)
Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer
Nadine S. Jahchan et al.
CELL REPORTS (2016)
Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer
Liyan Jiang et al.
PLOS GENETICS (2016)
PI3 Kinase Pathway and MET Inhibition is Efficacious in Malignant Pleural Mesothelioma
Rajani Kanteti et al.
SCIENTIFIC REPORTS (2016)
Role of copper transporters in platinum resistance
Deepak Kilari et al.
WORLD JOURNAL OF CLINICAL ONCOLOGY (2016)
LB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potential
Christopher S. Hong et al.
CANCER BIOLOGY & THERAPY (2015)
Protein Phosphatase 2A Inhibition with LB100 Enhances Radiation-Induced Mitotic Catastrophe and Tumor Growth Delay in Glioblastoma
Ira K. Gordon et al.
MOLECULAR CANCER THERAPEUTICS (2015)
Cross talk between PI3K-AKT-GSK-3 beta and PP2A pathways determines tau hyperphosphorylation
Yixuan Wang et al.
NEUROBIOLOGY OF AGING (2015)
HABP2 is a novel regulator of hyaluronan-mediated human lung cancer progression
Tamara Mirzapoiazova et al.
FRONTIERS IN ONCOLOGY (2015)
The Protein Phosphatase 2A Inhibitor LB100 Sensitizes Ovarian Carcinoma Cells to Cisplatin-Mediated Cytotoxicity
Ki-Eun Chang et al.
MOLECULAR CANCER THERAPEUTICS (2015)
Inhibition of protein phosphatase 2A sensitizes pancreatic cancer to chemotherapy by increasing drug perfusion via HIF-1α-VEGF mediated angiogenesis
Xueli Bai et al.
CANCER LETTERS (2014)
Protein phosphatase 2A promotes hepatocellular carcinogenesis in the diethylnitrosamine mouse model through inhibition of p53
Francois H. T. Duong et al.
CARCINOGENESIS (2014)
Targeting Epithelial-to-Mesenchymal Transition with Met Inhibitors Reverts Chemoresistance in Small Cell Lung Cancer
Israel Canadas et al.
CLINICAL CANCER RESEARCH (2014)
In vivo discovery of immunotherapy targets in the tumour microenvironment
Penghui Zhou et al.
NATURE (2014)
MET and PI3K/mTOR as a Potential Combinatorial Therapeutic Target in Malignant Pleural Mesothelioma
Rajani Kanteti et al.
PLOS ONE (2014)
Inhibition of protein phosphatase 2A with a small molecule LB100 radiosensitizes nasopharyngeal carcinoma xenografts by inducing mitotic catastrophe and blocking DNA damage repair
Peng Lv et al.
ONCOTARGET (2014)
Paxillin mutations affect focal adhesions and lead to altered mitochondrial dynamics: Relevance to lung cancer
Ichiro Kawada et al.
CANCER BIOLOGY & THERAPY (2013)
Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair
Dongping Wei et al.
CLINICAL CANCER RESEARCH (2013)
Protein phosphatase 2A: a target for anticancer therapy
Danilo Perrotti et al.
LANCET ONCOLOGY (2013)
Silencing PP2A Inhibitor by Lenti-shRNA Interference Ameliorates Neuropathologies and Memory Deficits in tg2576 Mice
Gong-Ping Liu et al.
MOLECULAR THERAPY (2013)
Assay of the Multiple Energy-Producing Pathways of Mammalian Cells
Barry R. Bochner et al.
PLOS ONE (2011)
Pharmacologic Modulation of Serine/Threonine Phosphorylation Highly Sensitizes PHEO in a MPC Cell and Mouse Model to Conventional Chemotherapy
Lucia Martiniova et al.
PLOS ONE (2011)
A synthetic cantharidin analog for the enhancement of doxorubicin suppression of stem cell-derived aggressive sarcoma
Chao Zhang et al.
BIOMATERIALS (2010)
Hypoxia, inflammation, and the tumor microenvironment in metastatic disease
Elizabeth C. Finger et al.
CANCER AND METASTASIS REVIEWS (2010)
EphA2 Mutation in Lung Squamous Cell Carcinoma Promotes Increased Cell Survival, Cell Invasion, Focal Adhesions, and Mammalian Target of Rapamycin Activation
Leonardo Faoro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms
Jie Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Role of c-Met in Cancer: Emphasis on Lung Cancer
Ravi Salgia
SEMINARS IN ONCOLOGY (2009)
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
Ben Langmead et al.
GENOME BIOLOGY (2009)
HGF increases cisplatin resistance via down-regulation of AlF in lung cancer cells
Jin-Tang Chen et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2008)
Expression and Mutational Analysis of MET in Human Solid Cancers
Patrick C. Ma et al.
GENES CHROMOSOMES & CANCER (2008)
Molecular mechanisms of resistance and toxicity associated with platinating agents
Cara A. Rabik et al.
CANCER TREATMENT REVIEWS (2007)
Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
Ting-Chao Chou
PHARMACOLOGICAL REVIEWS (2006)
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms
RV Parry et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Bi-directional regulation of Ser-985 phosphorylation of c-Met via protein kinase C and protein phosphatase 2A involves c-Met activation and cellular responsiveness to hepatocyte growth factor
A Hashigasako et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A
FHT Duong et al.
GASTROENTEROLOGY (2004)
分享论文
