期刊
MICROSCOPY RESEARCH AND TECHNIQUE
卷 85, 期 1, 页码 202-208出版社
WILEY
DOI: 10.1002/jemt.23896
关键词
antibacterial activity; Au nanoparticles; phytochemicals; Ricinus communis L
The phytochemical tests of Ricinus communis L methanolic extract revealed the presence of certain compounds, and gold nanoparticles were successfully synthesized from the extract. Antibacterial tests against different strains showed inhibitory effects on specific bacteria by the extract and nanoparticles.
In the current research study, the phytochemical tests of the Ricinus communis L methanolic extract detected the presence of coumarin, reducing sugar, emodines, terpenoids, flavonoids, and steroids while water extract showed the presence of alkaloids, terpenoids, steroids, and soluble starch. The methanolic extract was further subjected to synthesize Au nanoparticles. The synthesized nanoparticles were confirmed by UV-Vis through the appearance of a peak at 550 nm which correspond to the existence of Au nanoparticles. The size and morphology of synthesized nanoparticle were further studied by the dynamic light scattering technique which shows that nanoparticles were in the range of 100 nm which were further confirmed by transmission electron microscopy. The synthesized nanoparticles and extracts were tested against different bacterial strains. The results revealed that methanolic extract showed maximum inhibition of 19.5 mm against Klebsiella pneumoniae and 20.33 mm against Bacillus cereus while water extract showed maximum inhibition of 18.16 mm against Pseudomonas aeruginosa and 19.33 mm against B. cereus. On the other hand, Au nanoparticles showed maximum inhibition of 18.5 mm against Escherichia coli.
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