期刊
MICROCHIMICA ACTA
卷 188, 期 9, 页码 -出版社
SPRINGER WIEN
DOI: 10.1007/s00604-021-04964-1
关键词
Plasmon; Gold nanostructure; Biosensing; Bioimaging; Scattering; Photothermal; Photoacoustic
资金
- National Natural Science Foundation of China [22004029, 32001785]
- Scientific Research Project of Education Department of Hubei Province [Q20203003]
Plasmonic gold nanostructures, with unique optical properties and good biocompatibility, are ideal for developing methods in biosensing and bioimaging. This review summarizes the applications and techniques of biosensing and bioimaging in vitro and in vivo using plasmonic gold nanostructures.
As one kind of noble metal nanostructures, the plasmonic gold nanostructures possess unique optical properties as well as good biocompatibility, satisfactory stability, and multiplex functionality. These distinctive advantages make the plasmonic gold nanostructures an ideal medium in developing methods for biosensing and bioimaging. In this review, the optical properties of the plasmonic gold nanostructures were firstly introduced, and then biosensing in vitro based on localized surface plasmon resonance, Rayleigh scattering, surface-enhanced fluorescence, and Raman scattering were summarized. Subsequently, application of the plasmonic gold nanostructures for in vivo bioimaging based on scattering, photothermal, and photoacoustic techniques has been also briefly covered. At last, conclusions of the selected examples are presented and an outlook of this research topic is given.
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