4.7 Article

The Diversity of Vaginal Microbiota Predicts Neoadjuvant Chemotherapy Responsiveness in Locally Advanced Cervical Cancer

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Summary: This study showed that there are significant differences in vaginal microbiota between patients with cervical cancer and healthy individuals, suggesting a potential association between specific microbial abundance and the advancement of cervical cancer. Lactobacillus and Gardnerella were found to be significantly different between healthy controls and cervical intraepithelial neoplasia patients, while Streptococcus exhibited differential abundance in invasive cervical cancer patients compared to CIN patients. Additionally, the diagnostic abilities of Gardnerella and Streptococcus in predicting cervical cancer progression demonstrated high performance.

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