4.7 Article

Engineering the permeability of Halomonas bluephagenesis enhanced its chassis properties

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Summary: The outer membrane of Gram-negative bacteria is a crucial component that provides cell rigidity and acts as a permeability barrier. The regulation of lipid A biogenesis is essential in maintaining asymmetrical bilayer structure of the membrane. Disruption of this process can lead to new targets for antibiotics to combat resistance mechanisms.

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