MgO and MWCNTs amplified electrochemical sensor for guanine, adenine and epinephrine

In the present study, magnesium oxide and multi-walled carbon nanotubes modified carbon paste electrode (MgO-MWCNTs-MCPE) utilized for specific and simultaneous investigation of guanine (GA), adenine (AD) and epinephrine (EP). The MgO nanoparticles (NPs) was prepared by mechanochemical manner. Particle size, surface morphology and elemental analysis of MgO NPs was characterized by X-ray diffraction (XRD) and field emission scanning electron microscopy with energy dispersive X-ray (FESEM- EDX). The electrochemical deeds of the GA, AD and EP were studied by cyclic voltammetry (CV), Linear sweep voltammetry (LSV) and differential pulse voltammetry (DPV) at MgO-MWCNTs-MCPE. The exterior structures of unmodified carbon paste electrode (UCPE), MgO-MCPE and MgO-MWCNTs-MCPE were also studied by FESEM. The specific parameters including pH solution, varying speed rate and concentration of analytes were optimized at MgO-MWCNTs-MCPE. The electrode process was originated to be adsorption controlled movement and the detection limit (LOD) for GA, AD and EP was attained at 0.92, 1.49 and 0.83 mu M respectively. The established electrode also contributed very good stability and reproducibility. The MgO-MWCNTs-MCPE portrays the very fine interface with these biological molecules and displayed the sufficient sensitivity and selectivity for individual and simultaneous study.

Automated summary

The MgO-MWCNTs-MCPE was used in this study for the specific and simultaneous investigation of guanine, adenine, and epinephrine. By optimizing specific parameters and employing electrochemical methods, satisfactory results were obtained in terms of sensitivity and selectivity.