4.7 Review

Nanoparticle-Mediated STING Agonist Delivery for Enhanced Cancer Immunotherapy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Medicine, Research & Experimental

cGAS-STING signaling in cancer immunity and immunotherapy

Huashan Du et al.

Summary: Recent studies have revealed that the cGAS-STING pathway plays a crucial role in antitumor immunity, promoting senescence and apoptosis of cancer cells while enhancing the protective effects of cytotoxic T cells and natural killer cells. Combining the cGAS-STING signaling pathway with other therapeutic methods offers a new perspective for overcoming obstacles in its application.

BIOMEDICINE & PHARMACOTHERAPY (2021)

Article Chemistry, Multidisciplinary

Chemo-physical Strategies to Advance the in Vivo Functionality of Targeted Nanomedicine: The Next Generation

Junjie Li et al.

Summary: The text emphasizes the evolution of nanomedicine from biologically inert entities to smarter systems aimed at advancing in vivo functionality. It highlights the importance of focusing on nano-bio interactions and desirable functionality in tissue, cellular, and molecular levels, as well as providing definitive evidence for proof-of-mechanism.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Review Biotechnology & Applied Microbiology

Engineering precision nanoparticles for drug delivery

Michael J. Mitchell et al.

Summary: The development of nanoparticles has shown promising clinical applications, overcoming the limitations of therapeutic interventions and biological barriers. Precision therapies have enhanced treatment efficacy through personalized interventions. Advancements in nanoparticle design aim to optimize drug delivery, improving efficacy in general applications and enabling tailored designs for precision applications.

NATURE REVIEWS DRUG DISCOVERY (2021)

Review Chemistry, Medicinal

STING, a promising target for small molecular immune modulator: A review

Yijun Liu et al.

Summary: STING is a crucial player in the human innate immune system, activating production of interferons and cytokines to combat infections, inflammation, and tumorigenesis. Research focuses on STING's structure, function, regulation, and small molecule modulators for potential therapeutic applications.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

Nanoparticle delivery improves the pharmacokinetic properties of cyclic dinucleotide STING agonists to open a therapeutic window for intravenous administration

Mohamed Wehbe et al.

Summary: The STING pathway is crucial in cancer immunosurveillance and STING-NPs show promising potential in remodeling TME and enhancing immunotherapy responses. Nanocarrier delivery of cGAMP improves its accumulation in tumors and activation of STING pathway, resulting in reprogramming of TME towards an immunogenic milieu with increased T-cell infiltration and improved response to immunotherapy.

JOURNAL OF CONTROLLED RELEASE (2021)

Article Biochemistry & Molecular Biology

Tuning the Innate Immune Response to Cyclic Dinucleotides by Using Atomic Mutagenesis

Yao Li et al.

CHEMBIOCHEM (2020)

Article Engineering, Biomedical

Multifunctional STING-Activating Mn3O4@Au-dsDNA/DOX Nanoparticle for Antitumor Immunotherapy

Min Zhou et al.

ADVANCED HEALTHCARE MATERIALS (2020)

Article Chemistry, Multidisciplinary

Engineering Polymeric Prodrug Nanoplatform for Vaccination Immunotherapy of Cancer

Lei Zhou et al.

NANO LETTERS (2020)

Review Chemistry, Multidisciplinary

Nano-Immune-Engineering Approaches to Advance Cancer Immunotherapy: Lessons from Ultra-pH-Sensitive Nanoparticles

Suxin Li et al.

ACCOUNTS OF CHEMICAL RESEARCH (2020)

Review Pharmacology & Pharmacy

Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval

Duhyeong Hwang et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

Article Multidisciplinary Sciences

Nanoparticle-enhanced chemo-immunotherapy to trigger robust antitumor immunity

Jingjing Liang et al.

SCIENCE ADVANCES (2020)

Review Medicine, General & Internal

Challenges and Opportunities in the Clinical Development of STING Agonists for Cancer Immunotherapy

Leila Motedayen Aval et al.

JOURNAL OF CLINICAL MEDICINE (2020)

Article Multidisciplinary Sciences

Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window

Xu Wang et al.

NATURE COMMUNICATIONS (2020)

Article Multidisciplinary Sciences

Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic

Emily N. Chin et al.

SCIENCE (2020)

Article Multidisciplinary Sciences

Structural basis of STING binding with and phosphorylation by TBK1

Conggang Zhang et al.

NATURE (2019)

Article Medicine, Research & Experimental

An Analysis of the Expression and Association with Immune Cell Infiltration of the cGAS/STING Pathway in Pan-Cancer

Xiang An et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2019)

Review Oncology

Activating cGAS-STING pathway for the optimal effect of cancer immunotherapy

Anping Li et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)

Article Chemistry, Medicinal

Discovery and Mechanistic Study of a Novel Human-Stimulator-of-Interferon-Genes Agonist

Xiaohui Zhang et al.

ACS INFECTIOUS DISEASES (2019)

Review Nanoscience & Nanotechnology

Cancer nanomedicine for combination cancer immunotherapy

Jutaek Nam et al.

NATURE REVIEWS MATERIALS (2019)

Review Immunology

STING pathway agonism as a cancer therapeutic

Blake A. Flood et al.

IMMUNOLOGICAL REVIEWS (2019)

Article Nanoscience & Nanotechnology

Smart cancer nanomedicine

Roy van der Meel et al.

NATURE NANOTECHNOLOGY (2019)

Review Medicine, Research & Experimental

STING activation in cancer immunotherapy

Ting Su et al.

THERANOSTICS (2019)

Article Nanoscience & Nanotechnology

Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy

David R. Wilson et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2018)

Article Chemistry, Medicinal

Identification of -Mangostin as an Agonist of Human STING

Yibo Zhang et al.

CHEMMEDCHEM (2018)

Editorial Material Immunology

Tumor cGAMP Awakens the Natural Killers

Shriram K. Sundararaman et al.

IMMUNITY (2018)

Review Cell Biology

STING Signaling Promotes Apoptosis, Necrosis, and Cell Death: An Overview and Update

Song Liu et al.

MEDIATORS OF INFLAMMATION (2018)

Article Multidisciplinary Sciences

Design of amidobenzimidazole STING receptor agonists with systemic activity

Joshi M. Ramanjulu et al.

NATURE (2018)

Review Immunology

STING Signaling in Cancer Cells: Important or Not?

Olga Sokolowska et al.

ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS (2018)

Article Nanoscience & Nanotechnology

A STING-activating nanovaccine for cancer immunotherapy

Min Luo et al.

NATURE NANOTECHNOLOGY (2017)

Article Pharmacology & Pharmacy

A cell-based high throughput screening assay for the discovery of cGAS-STING pathway agonists

Bowei Liu et al.

ANTIVIRAL RESEARCH (2017)

Article Materials Science, Biomaterials

Liposomal Delivery Enhances Immune Activation by STING Agonists for Cancer Immunotherapy

Sandeep T. Koshy et al.

ADVANCED BIOSYSTEMS (2017)

Article Multidisciplinary Sciences

Activation of STING requires palmitoylation at the Golgi

Kojiro Mukai et al.

NATURE COMMUNICATIONS (2016)

Review Chemistry, Multidisciplinary

New Developments in Liposomal Drug Delivery

Bhushan S. Pattni et al.

CHEMICAL REVIEWS (2015)

Review Immunology

STING: infection, inflammation and cancer

Glen N. Barber

NATURE REVIEWS IMMUNOLOGY (2015)

Article Chemistry, Multidisciplinary

A new adjuvant delivery system 'cyclic di-GMP/YSK05 liposome' for cancer immunotherapy

Hiroko Miyabe et al.

JOURNAL OF CONTROLLED RELEASE (2014)

Article Biochemistry & Molecular Biology

Hydrolysis of 2′3′-cGAMP by ENPP1 and design of nonhydrolyzable analogs

Lingyin Li et al.

NATURE CHEMICAL BIOLOGY (2014)

Review Food Science & Technology

Type I Interferons as Regulators of Human Antigen Presenting Cell Functions

Sandra Gessani et al.

TOXINS (2014)

Article Biochemistry & Molecular Biology

Anticancer Flavonoids Are Mouse-Selective STING Agonists

Sujeong Kim et al.

ACS CHEMICAL BIOLOGY (2013)

Review Biochemistry & Molecular Biology

Cyclic Dinucleotides and the Innate Immune Response

Olga Danilchanka et al.

Article Biochemistry & Molecular Biology

Species-specific detection of the antiviral small-molecule compound CMA by STING

Taner Cavlar et al.

EMBO JOURNAL (2013)

Review Immunology

Immune Sensing of DNA

Soren R. Paludan et al.

IMMUNITY (2013)

Review Pharmacology & Pharmacy

Block copolymer micelles for drug delivery: Design, characterization and biological significance

Kazunori Kataoka et al.

ADVANCED DRUG DELIVERY REVIEWS (2012)

Review Chemistry, Multidisciplinary

Polymersomes for drug delivery: Design, formation and characterization

Jung Seok Lee et al.

JOURNAL OF CONTROLLED RELEASE (2012)

Review Chemistry, Multidisciplinary

Liposomes: From a Clinically Established Drug Delivery System to a Nanoparticle Platform for Theranostic Nanomedicine

Wafa' T. Al-Jamal et al.

ACCOUNTS OF CHEMICAL RESEARCH (2011)

Review Biochemistry & Molecular Biology

Stimuli-Responsive Polymersomes as Nanocarriers for Drug and Gene Delivery

Ozana Onaca et al.

MACROMOLECULAR BIOSCIENCE (2009)

Article Multidisciplinary Sciences

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

Hiroki Ishikawa et al.

NATURE (2009)

Article Multidisciplinary Sciences

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa et al.

NATURE (2008)