期刊
FRONTIERS IN BIOSCIENCE-LANDMARK
卷 21, 期 -, 页码 1372-1392出版社
FRONTIERS IN BIOSCIENCE INC
DOI: 10.2741/4462
关键词
Heparin; Anticoagulation; Anticoagulants; Bovine Heparin; Bioengineered Heparin; Review
资金
- National Institutes of Health [HL125371, HL094463, GM102137, HL62244, HL096972]
- Heparin Consortium
Heparin, a sulfated polysaccharide, has been used as a clinical anticoagulant for over 90 years. Newer anticoagulants, introduced for certain specialized applications, have not significantly displaced heparin and newer heparin-based anticoagulants in most medical procedures. This chapter, while reviewing anticoagulation and these newer anticoagulants, focuses on heparin-based anticoagulants, including unfractionated heparin, low molecular weight heparins and ultra-low molecular weight heparins. Heparin's structures and its biological and therapeutic roles are discussed. Particular emphasis is placed on heparin's therapeutic application and its adverse effects. The future prospects are excellent for new heparins and new heparin-based therapeutics with improved properties.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据