4.8 Article

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019

期刊

LANCET
卷 397, 期 10292, 页码 2337-2360

出版社

ELSEVIER SCIENCE INC
DOI: 10.1016/S0140-6736(21)01169-7

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资金

  1. Monash University, VIC, Australia
  2. International Centre for Casemix and Clinical Coding, Faculty of Medicine, National University of Malaysia
  3. Department of Health Policy and Management, Faculty of Public Health, Kuwait University
  4. Romanian National Authority for Scientific Research and Innovation (CNDS-UEFISCDI) [PN-III-P2-2.1-SOL-2020-2-0351]
  5. Alexander von Humboldt Foundation through the Alexander von Humboldt Professor award - German Federal Ministry of Education and Research
  6. National Institutes of Health (NIH) National Center for Advancing Translational Science (NCATS) UCLA [UL1TR001881]
  7. Oxford National Institute for Health Research (NIHR) Biomedical Research Centre (BRC)
  8. Portuguese national funds through Fundacao para a Ciencia e Tecnologia (FCT), IP [SFRH/BHD/110001/2015, DL57/2016/CP1334/CT0006]
  9. NIHR Applied Research Collaboration (ARC) South London at King's College Hospital NHS Foundation Trust
  10. Royal College of Physicians
  11. NIHR BRC based at Guy's and St Thomas' NHS Foundation Trust and King's College London
  12. FIU University Graduate School Dissertation Year Fellowship
  13. NIHR Applied Research Collaborations West Midland
  14. NIHR Global Health Research Unit on Improving Health in Slums at the University of Warwick
  15. UNC's Cancer Care Quality Training [2T32CA116339-11]
  16. National Heart Foundation of Australia
  17. NHMRC
  18. Ministry of Education Science and Technological Development of the Republic of Serbia [OI 175 014]
  19. Wellcome Trust/DBT India Alliance Fellowship [IA/CPHI/14/1/501497]
  20. NHS Research Scotland Senior Clinical Fellowship [SCAF/15/02]
  21. Medical Research Council [MC_UU_00022/2]
  22. Scottish Government Chief Scientist Office [SPHSU13]
  23. Manipal Academy of Higher Education
  24. UGC Centre of Advanced Study (CAS II)
  25. NIHR Oxford BRC
  26. BHF Oxford Centre of Research Excellence
  27. Secretaria Nacional de Ciencia, Tecnologia e Innovacion (SENACYT), Panama
  28. German Federal Ministry of Education and Research [01EA1808A]
  29. NIH National Cancer Institute [R01CA132115, R21CA235139-01]
  30. Breast Cancer Research Program from the Department of Defense [W81XWH1810605]
  31. Egyptian Fulbright Mission Program
  32. Ministry of Education, Science and Technological Development of the Republic of Serbia [175087]
  33. HDRUK BREATHE Hub
  34. Applied Molecular Biosciences Unit (UCIBIO) [UIDB/04378/2020]
  35. Portuguese national funds via FCT/MCTES
  36. International Graduate Research Scholarship, University of Tasmania
  37. NHMRC Early Career Fellowship
  38. NIHR Global Health Group on Addressing Smokeless Tobacco Use AMP
  39. Building Research Capacity in South Asia at the University of York
  40. Romanian National Authority for Scientific Research and Innovation (CNDS-UEFISCDI [PN-III-P2-2.1-SOL-2020-2-0351]
  41. UK Biobank
  42. U.S. Department of Defense (DOD) [W81XWH1810605] Funding Source: U.S. Department of Defense (DOD)

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Ending the global tobacco epidemic is a major challenge in global health, and strong policies should be implemented by countries. Despite a decrease in smoking rates from 1990 to 2019, there are still a large number of smokers globally, and smoking-related deaths and disease burden remain a major health risk factor.
Background Ending the global tobacco epidemic is a defining challenge in global health. Timely and comprehensive estimates of the prevalence of smoking tobacco use and attributable disease burden are needed to guide tobacco control efforts nationally and globally. Methods We estimated the prevalence of smoking tobacco use and attributable disease burden for 204 countries and territories, by age and sex, from 1990 to 2019 as part of the Global Burden of Diseases, Injuries, and Risk Factors Study. We modelled multiple smoking-related indicators from 3625 nationally representative surveys. We completed systematic reviews and did Bayesian meta-regressions for 36 causally linked health outcomes to estimate non-linear dose-response risk curves for current and former smokers. We used a direct estimation approach to estimate attributable burden, providing more comprehensive estimates of the health effects of smoking than previously available. Findings Globally in 2019, 1.14 billion (95% uncertainty interval 1.13-1.16) individuals were current smokers, who consumed 7.41 trillion (7.11-7.74) cigarette-equivalents of tobacco in 2019. Although prevalence of smoking had decreased significantly since 1990 among both males (27.5% [26. 5-28.5] reduction) and females (37.7% [35.4-39.9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0.99 billion (0.98-1.00) in 1990. Globally in 2019, smoking tobacco use accounted for 7.69 million (7.16-8.20) deaths and 200 million (185-214) disability-adjusted life-years, and was the leading risk factor for death among males (20.2% [19.3-21.1] of male deaths). 6.68 million [86.9%] of 7.69 million deaths attributable to smoking tobacco use were among current smokers. Interpretation In the absence of intervention, the annual toll of 7.69 million deaths and 200 million disability-adjusted life-years attributable to smoking will increase over the coming decades. Substantial progress in reducing the prevalence of smoking tobacco use has been observed in countries from all regions and at all stages of development, but a large implementation gap remains for tobacco control. Countries have a dear and urgent opportunity to pass strong, evidence-based policies to accelerate reductions in the prevalence of smoking and reap massive health benefits for their citizens. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd.

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