期刊
KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
卷 37, 期 10, 页码 910-917出版社
WILEY
DOI: 10.1002/kjm2.12406
关键词
dental calculus; DMFT index; liver transplantation; oral hygiene; panoramic radiography
资金
- Kaohsiung Medical University Hospital [KMUH109-9M36, KMUH108-8R38]
- Ministry of Science and Technology of Taiwan [106-2314-B-037-053-MY3]
The study found that LT candidates often have poor oral hygiene, with the presence of dental calculus linked to a worse prognosis. Patients who undergo LT have a higher survival rate, while those at Child-Pugh stages B and C, and those with a MELD score ≥ 25 have lower survival rates. Cross-disciplinary collaboration should be routine in evaluating oral hygiene in LT candidates.
Liver transplantation (LT) candidates often present with poor oral hygiene, which could potentially lead to systemic infections and sepsis owing to their cirrhotic state. In this study, we investigated the oral health status of LT candidates and propose guidance for the detection and treatment of encountered oral lesions among these patients. The decayed, missing, and filled teeth (DMFT) index was determined through oral examination. The presence of dental calculus was detected using panoramic radiography and defined by the radiopaque dental calculus (RDC). From January 2011 to August 2018, 56 LT candidates were enrolled with a median follow-up of 39 months. The overall mean numbers of decayed, missing, and filled teeth among these patients were 2.7 +/- 2.8, 10.9 +/- 8.3, and 5.4 +/- 4.5, respectively. Eighteen patients (32.1%) had RDC. The 5-year survival rates of all 56 patients was 57.7%, while that of those who either received LT (23 patients) or not were 82.1% and 39.8%, respectively. A Cox regression model revealed better overall survival of patients after LT (adjusted hazard ratio [aHR] = 0.067, p = 0.001), worse survival among patients with RDC (aHR = 3.468, p = 0.010), at Child-Pugh stages B and C (aHR for stage B = 11.889, p = 0.028; aHR for stage C = 19.257, p = 0.013) compared to patients at Child-Pugh stage A, and those with a model for end-stage liver disease (MELD) score >= 25 (aHR = 13.721, p = 0.018). This study demonstrates that RDC was associated with worse prognosis in LT candidates. We therefore recommend that interprofessional collaboration should be a routine preoperative procedure for the evaluation of oral hygiene among LT candidates.
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