4.5 Article

Characterization of Synthetic Peptide Therapeutics Using Liquid Chromatography-Mass Spectrometry: Challenges, Solutions, Pitfalls, and Future Perspectives

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Analytical

Differential Ion Mobility Separations of D/L Peptide Epimers

Francis Berthias et al.

Summary: Since the 1980s, D-amino acid-containing peptides (DAACPs) have been discovered in animals, showing tremendous functional specificity at extremely low levels. The introduction of the new technique differential IMS (FAIMS) has successfully separated all 18 pairs of epimer species, showcasing a 2.5X resolution increase compared to trapped IMS.

ANALYTICAL CHEMISTRY (2021)

Review Chemistry, Multidisciplinary

Ultraviolet Photodissociation Mass Spectrometry for Analysis of Biological Molecules

Jennifer S. Brodbelt et al.

CHEMICAL REVIEWS (2020)

Article Biotechnology & Applied Microbiology

Advances in oral peptide therapeutics

Daniel J. Drucker

NATURE REVIEWS DRUG DISCOVERY (2020)

Review Pharmacology & Pharmacy

Just how prevalent are peptide therapeutic products? A critical review

Yajie Zhang et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

Article Chemistry, Analytical

HPLC-UV-MS Analysis: A Source for Severe Oxidation Artifacts

Fritz Schweikart et al.

ANALYTICAL CHEMISTRY (2019)

Article Chemistry, Analytical

A Cyclic Ion Mobility-Mass Spectrometry System

Kevin Giles et al.

ANALYTICAL CHEMISTRY (2019)

Article Chemistry, Analytical

Multi-Attribute Method for Quality Control of Therapeutic Proteins

Sarah Rogstad et al.

ANALYTICAL CHEMISTRY (2019)

Article Biochemistry & Molecular Biology

Therapeutic peptides: Historical perspectives, current development trends, and future directions

Jolene L. Lau et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2018)

Article Chemistry, Analytical

Fast and Effective Ion Mobility-Mass Spectrometry Separation of D-Amino-Acid-Containing Peptides

Kevin Jeanne Dit Fouque et al.

ANALYTICAL CHEMISTRY (2017)

Review Chemistry, Medicinal

New and Evolving Techniques for the Characterization of Peptide Therapeutics

Suzanne M. D'Addio et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2016)

Review Pharmacology & Pharmacy

Strategic Approaches to Optimizing Peptide ADME Properties

Li Di

AAPS JOURNAL (2015)

Article Chemistry, Analytical

Discrimination of Leucine and lsoleucine in Peptides Sequencing with Orbitrap Fusion Mass Spectrometer

Albert T. Lebedev et al.

ANALYTICAL CHEMISTRY (2014)

Review Chemistry, Analytical

Related impurities in peptide medicines

Matthias D'Hondt et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2014)

Article Biochemical Research Methods

Residual metals cause variability in methionine oxidation measurements in protein pharmaceuticals using LC-UV/MS peptide mapping

Li Zang et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2012)

Review Spectroscopy

Differentiation of isomeric amino acid residues in proteins and peptides using mass spectrometry

Pilar Perez Hurtado et al.

MASS SPECTROMETRY REVIEWS (2012)

Article Chemistry, Analytical

Identification of Racemization Sites Using Deuterium Labeling and Tandem Mass Spectrometry

Lihua Huang et al.

ANALYTICAL CHEMISTRY (2010)

Review Chemistry, Analytical

Biomolecule Analysis by Ion Mobility Spectrometry

Brian C. Bohrer et al.

ANNUAL REVIEW OF ANALYTICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Formation of Fmoc-β-alanine during Fmoc-protections with Fmoc-OSu

Markus Obkircher et al.

JOURNAL OF PEPTIDE SCIENCE (2008)

Article Chemistry, Analytical

18O labeling method for identification and quantification of succinimide in proteins

Gang Xiao et al.

ANALYTICAL CHEMISTRY (2007)

Article Biochemical Research Methods

How to discriminate between leucine and isoleucine by low energy ESI-TRAP MSn

Andrea Armirotti et al.

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2007)

Article Biochemical Research Methods

Differentiation of aspartic and isoaspartic acids using electron transfer dissociation

PB O'Connor et al.

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2006)

Article Biotechnology & Applied Microbiology

Large-scale manufacture of peptide therapeutics by chemical synthesis

BL Bray

NATURE REVIEWS DRUG DISCOVERY (2003)