The ARIC (Atherosclerosis Risk In Communities) Study JACC Focus Seminar 3/8

ARIC (Atherosclerosis Risk In Communities) initiated community-based surveillance in 1987 for myocardial infarction and coronary heart disease (CHD) incidence and mortality and created a prospective cohort of 15,792 Black and White adults ages 45 to 64 years. The primary aims were to improve understanding of the decline in CHD mortality and identify determinants of subclinical atherosclerosis and CHD in Black and White middle-age adults. ARIC has examined areas including health disparities, genomics, heart failure, and prevention, producing more than 2,300 publications. Results have had strong clinical impact and demonstrate the importance of population-based research in the spectrum of biomedical research to improve health. (J Am Coll Cardiol 2021;77:2939-59) Published by Elsevier on behalf of the American College of Cardiology Foundation.

Automated summary

The ARIC project, initiated in 1987, focuses on community-based surveillance for myocardial infarction and coronary heart disease, aiming to understand the decline in CHD mortality and identify determinants of subclinical atherosclerosis and CHD in middle-aged Black and White adults. Through research in areas such as health disparities, genomics, heart failure, and prevention, ARIC has published over 2,300 papers with significant clinical impact, highlighting the importance of population-based research in improving health.