期刊
JOURNAL OF PSYCHOSOMATIC RESEARCH
卷 147, 期 -, 页码 -出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jpsychores.2021.110537
关键词
Coeliac disease; Psychosocial; Quality of life; Systematic review
类别
资金
- Australian Government Research Training Program Scholarship
In adults with coeliac disease, quality of life is associated with depression, anxiety, illness perceptions, coping, and attitudes/behaviors towards food and the gluten-free diet. These psychosocial factors may directly or indirectly impact quality of life by influencing psychological well-being and adherence to the gluten-free diet. Further research is needed to explore these interconnected processes and identify targets for psychosocial interventions.
Background: Individuals living with coeliac disease generally experience a remission of symptoms after adopting the gluten-free diet but often report substantial treatment burden and ongoing quality of life issues. Psychosocial factors have been suggested to play a significant role in post-diagnosis quality of life but have yet to be systematically reviewed. Aim: To review the evidence for psychosocial factors associated with quality of life in adult coeliac disease cohorts. Methods: Studies were identified via systematic searches of eight databases (MEDLINE, Embase, Emcare, PsycINFO, Ovid Nursing, CINAHL, Informit Health Collection, Cochrane Library) in May 2019. Results: Fourteen studies were included involving 3372 participants (80.2% female, mean age = 46.4 years). Symptoms of depression and anxiety were the most examined psychosocial factors across all studies. Quality of life was differentially associated with psychological distress, illness perceptions, coping, and attitudes/behaviours regarding food and the gluten-free diet. Conclusion: Several psychosocial factors are associated with quality of life in adults living with coeliac disease. Current evidence suggests these factors are interrelated and may influence quality of life directly, via reduced psychological well-being, and indirectly, via reduced adherence to the gluten-free diet. Future research is needed to examine these processes concurrently, with the aim of elucidating the psychosocial mechanisms underlying post-diagnosis well-being and identifying potential targets for psychosocial intervention.
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