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Discovery Proteomics for COVID-19: Where We Are Now

期刊

JOURNAL OF PROTEOME RESEARCH
卷 20, 期 10, 页码 4627-4639

出版社

AMER CHEMICAL SOC
DOI: 10.1021/acs.jproteome.1c00475

关键词

proteomics; COVID-19; SARS-CoV-2; biomarkers; plasma; biofluids; mass spectrometry

资金

  1. Cedars-Sinai Medical Center
  2. Erika J. Glazer Family Foundation
  3. CSMC Precision Health Grant

向作者/读者索取更多资源

The study summarizes proteomic research on hallmark proteins associated with COVID-19, as well as the highly variable humoral response and increased risk of autoimmunity in the disease.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible coronavirus responsible for the pandemic coronavirus disease 2019 (COVID-19), which has had a devastating impact on society. Here, we summarize proteomic research that has helped elucidate hallmark proteins associated with the disease with respect to both short- and long-term diagnosis and prognosis. Additionally, we review the highly variable humoral response associated with COVID-19 and the increased risk of autoimmunity.

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