Palladium-Catalyzed One-Pot Synthesis of Pyrroloindolines from 2-Alkynyl Arylazides and Thioacetamides

A novel and efficient synthetic method for the preparation of various pyrroloindolines from 2-alkynyl arylazides and thioacetamides was developed. The reaction was carried out in a one-pot process under mild reaction conditions to afford the products in moderate to good yields, which has the potential to be used in organic synthesis.

Automated summary

A novel and efficient synthetic method was developed for the preparation of various pyrroloindolines from 2-alkynyl arylazides and thioacetamides. The reaction was carried out in a one-pot process under mild reaction conditions to afford the products in moderate to good yields, showing potential for use in organic synthesis.