Autoimmune neurology: Co-occurrence of anti-NMDAR encephalitis and anti-MOG associated disease, report of a case

We report the case of a patient with symptoms of anti-NMDAR encephalitis and anti-MOG associated disease simultaneously, in whom the identification of antibodies guided to a more aggressive treatment strategy, resulting in a good clinical outcome. MRI is an important tool to diagnose this kind of patients. The co-occurrence of both diseases in infrequent, but atypical symptoms should increase our awareness of the possibility of an overlap syndrome.

Automated summary

In this case report, a patient with symptoms of both anti-NMDAR encephalitis and anti-MOG associated disease was treated with a more aggressive strategy guided by antibody identification, leading to a good clinical outcome. MRI is a crucial tool for diagnosing such patients. Although the co-occurrence of both diseases is rare, atypical symptoms should raise awareness of the possibility of an overlap syndrome.