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CELL METABOLISM (2013)
Combined Deficiency in Glutathione Peroxidase 4 and Vitamin E Causes Multiorgan Thrombus Formation and Early Death in Mice
Markus Wortmann et al.
CIRCULATION RESEARCH (2013)
Ibuprofen and Lipoic Acid Conjugate Neuroprotective Activity Is Mediated by Ngb/Akt Intracellular Signaling Pathway in Alzheimer's Disease Rat Model
Susi Zara et al.
GERONTOLOGY (2013)
Iron regulation by hepcidin
Ningning Zhao et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Vitamin E: tocopherols and tocotrienols as potential radiation countermeasures
Vijay K. Singh et al.
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Enhanced Brain Delivery of Deferasirox-Lactoferrin Conjugates for Iron Chelation Therapy in Neurodegenerative Disorders: In Vitro and in Vivo Studies
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MOLECULAR PHARMACEUTICS (2013)
Intranasal deferoxamine reverses iron-induced memory deficits and inhibits amyloidogenic APP processing in a transgenic mouse model of Alzheimer's disease
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NEUROBIOLOGY OF AGING (2013)
Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain
Chuang Guo et al.
NEUROCHEMISTRY INTERNATIONAL (2013)
Increased expression of ferritin in cerebral cortex after human traumatic brain injury
Huan-Dong Liu et al.
NEUROLOGICAL SCIENCES (2013)
A delicate balance: Iron metabolism and diseases of the brain
Dominic Hare et al.
FRONTIERS IN AGING NEUROSCIENCE (2013)
The systemic iron-regulatory proteins hepcidin and ferroportin are reduced in the brain in Alzheimer's disease
Animesh Alexander Raha et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2013)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Scott J. Dixon et al.
CELL (2012)
Deferiprone Reduces Amyloid-β and Tau Phosphorylation Levels but not Reactive Oxygen Species Generation in Hippocampus of Rabbits Fed a Cholesterol-Enriched Diet
Jaya R. P. Prasanthi et al.
JOURNAL OF ALZHEIMERS DISEASE (2012)
Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export
Peng Lei et al.
NATURE MEDICINE (2012)
An Investigation of Age-Related Iron Deposition Using Susceptibility Weighted Imaging
Dan Wang et al.
PLOS ONE (2012)
Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study
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ALZHEIMERS RESEARCH & THERAPY (2012)
Brain Iron Quantification in Mild Traumatic Brain Injury: A Magnetic Field Correlation Study
E. Raz et al.
AMERICAN JOURNAL OF NEURORADIOLOGY (2011)
A pilot trial of deferiprone for neurodegeneration with brain iron accumulation
Giovanni Abbruzzese et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2011)
Iron(II) Binding to Amyloid-β, the Alzheimer's Peptide
Fatima Bousejra-ElGarah et al.
INORGANIC CHEMISTRY (2011)
Iron Promotes the Toxicity of Amyloid β Peptide by Impeding Its Ordered Aggregation
Beinan Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Expression and Localization of Mitochondrial Ferritin mRNA in Alzheimer's Disease Cerebral Cortex
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PLOS ONE (2011)
Delineating the Role of Glutathione Peroxidase 4 in Protecting Cells Against Lipid Hydroperoxide Damage and in Alzheimer's Disease
Min-Hyuk Yoo et al.
ANTIOXIDANTS & REDOX SIGNALING (2010)
Dietary Antioxidants and Long-term Risk of Dementia
Elizabeth E. Devore et al.
ARCHIVES OF NEUROLOGY (2010)
Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease
James A. Duce et al.
CELL (2010)
Oxidative stress and Alzheimer's disease: dietary polyphenols as potential therapeutic agents
Altaf S. Darvesh et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2010)
Selective Translational Control of the Alzheimer Amyloid Precursor Protein Transcript by Iron Regulatory Protein-1
Hyun-Hee Cho et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Oxidative Stress in the Progression of Alzheimer Disease in the Frontal Cortex
Mubeen A. Ansari et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2010)
APOE4 Allele Disrupts Resting State fMRI Connectivity in the Absence of Amyloid Plaques or Decreased CSF Aβ42
Yvette I. Sheline et al.
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Ternary Complexes of Iron, Amyloid-β, and Nitrilotriacetic Acid: Binding Affinities, Redox Properties, and Relevance to Iron-Induced Oxidative Stress in Alzheimer's Disease
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BIOCHEMISTRY (2009)
Fenton chemistry and oxidative stress mediate the toxicity of the β-amyloid peptide in a Drosophila model of Alzheimer's disease
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EUROPEAN JOURNAL OF NEUROSCIENCE (2009)
γ-Secretase: Successive Tripeptide and Tetrapeptide Release from the Transmembrane Domain of β-Carboxyl Terminal Fragment
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Age-related Iron Deposition in the Basal Ganglia: Quantitative Analysis in Healthy Subjects
Domenico Aquino et al.
RADIOLOGY (2009)
The effect of curcumin (turmeric) on Alzheimer's disease: An overview
Shrikant Mishra et al.
ANNALS OF INDIAN ACADEMY OF NEUROLOGY (2008)
Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease
Jack T. Rogers et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2008)
Neuroprotective actions of deferiprone in cultured cortical neurones and SHSY-5Y cells
Francisco Molina-Holgado et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Hepcidin Regulation of Iron Transport
Janics E. Collins et al.
JOURNAL OF NUTRITION (2008)
Antioxidant vitamin supplement use and risk of dementia or Alzheimer's disease in older adults
Shelly L. Gray et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2008)
The function of melanotransferrin: a role in melanoma cell proliferation and tumorigenesis
L. L. Dunn et al.
CARCINOGENESIS (2006)
Protective effect of N-acetyl-L-cysteine on amyloid β-peptide-induced learning and memory deficits in mice
Ai-Ling Fu et al.
BRAIN RESEARCH (2006)
Iron chelation in the biological activity of curcumin
Y Jiao et al.
FREE RADICAL BIOLOGY AND MEDICINE (2006)
Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice
R Reliene et al.
CARCINOGENESIS (2006)
Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Aβ peptides
XD Huang et al.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2004)
Molecular basis of vitamin E action - Tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting A beta amyloid deposition and toxicity in Alzheimer disease - A pilot phase 2 clinical trial
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ARCHIVES OF NEUROLOGY (2003)
An iron-responsive element type II in the 5′-untranslated region of the Alzheimer's amyloid precursor protein transcript
JT Rogers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Controlled trial of N-acetyleysteine for patients with probable Alzheimer's disease
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NEUROLOGY (2001)
Serum melanotransferrin, p97 as a biochemical marker of Alzheimer's disease
DK Kim et al.
NEUROPSYCHOPHARMACOLOGY (2001)
Treatment with a copper-zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice
RA Cherny et al.
NEURON (2001)
Iron, neuromelanin and ferritin content in the substantia nigra of normal subjects at different ages:: consequences for iron storage and neurodegenerative processes
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JOURNAL OF NEUROCHEMISTRY (2001)
Brain iron transport and neurodegeneration
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TRENDS IN MOLECULAR MEDICINE (2001)
Redox-active iron mediates amyloid-β toxicity
CA Rottkamp et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
In vivo evaluation of brain iron in Alzheimer disease using magnetic resonance imaging
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