相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。An in vitro toolbox to accelerate anti-malarial drug discovery and development
Susan A. Charman et al.
MALARIA JOURNAL (2020)
The past, present and future of anti-malarial medicines
Edwin G. Tse et al.
MALARIA JOURNAL (2019)
The Development Process for Discovery and Clinical Advancement of Modern Antimalarials
Trent D. Ashton et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
The Rebirth of Matrix Metalloproteinase Inhibitors: Moving Beyond the Dogma
Gregg B. Fields
CELLS (2019)
Resistance to Artemisinin Combination Therapies (ACTs): Do Not Forget the Partner Drug!
Christian Nsanzabana
TROPICAL MEDICINE AND INFECTIOUS DISEASE (2019)
Safety Assessment of Acyl Glucuronides-A Simplified Paradigm
Dennis A. Smith et al.
DRUG METABOLISM AND DISPOSITION (2018)
New developments in anti-malarial target candidate and product profiles
Jeremy N. Burrows et al.
MALARIA JOURNAL (2017)
Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase
Tanya Paquet et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Acyl glucuronide metabolites: Implications for drug safety assessment
Terry R. Van Vleet et al.
TOXICOLOGY LETTERS (2017)
malERA: An updated research agenda for insecticide and drug resistance in malaria elimination and eradication
Thomas Churcher et al.
PLOS MEDICINE (2017)
Single dose treatment of malaria - current status and perspectives
Johannes Mischlinger et al.
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2016)
Analysis of the dose-dependent stage-specific in vitro efficacy of a multi-stage malaria vaccine candidate cocktail
Alexander Boes et al.
MALARIA JOURNAL (2016)
Large-scale production of Plasmodium falciparum gametocytes for malaria drug discovery
Sandra Duffy et al.
NATURE PROTOCOLS (2016)
Subtle Changes in Endochin-Like Quinolone Structure Alter the Site of Inhibition within the Cytochrome bc1 Complex of Plasmodium falciparum
Allison M. Stickles et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
A novel multiple-stage antimalarial agent that inhibits protein synthesis
Beatriz Baragana et al.
NATURE (2015)
Hit and lead criteria in drug discovery for infectious diseases of the developing world
Kei Katsuno et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
Malaria medicines: a glass half full?
Timothy N. C. Wells et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria
Margaret A. Phillips et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
A One-Pot, Transition-Metal-Free Procedure for C-O, C-S, and C-N Bond Formation at the Benzylic Position of Methylarenes
Hiroyuki Shimojo et al.
SYNTHESIS-STUTTGART (2015)
Discovery of Novel, Highly Potent, and Selective Quinazoline-2-carboxamide-Based Matrix Metalloproteinase (MMP)-13 Inhibitors without a Zinc Binding Group Using a Structure-Based Design Approach
Hiroshi Nara et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
A novel approach for the discovery of chemically diverse anti-malarial compounds targeting the Plasmodium falciparum Coenzyme A synthesis pathway
Sabine Fletcher et al.
MALARIA JOURNAL (2014)
Identification of inhibitors of Plasmodium falciparum gametocyte development
Sandra Duffy et al.
MALARIA JOURNAL (2013)
Development and Optimization of a Novel 384-Well Anti-Malarial Imaging Assay Validated for High-Throughput Screening
Sandra Duffy et al.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2012)
P. falciparum In Vitro Killing Rates Allow to Discriminate between Different Antimalarial Mode-of-Action
Laura M. Sanz et al.
PLOS ONE (2012)
Improvement in Aqueous Solubility in Small Molecule Drug Discovery Programs by Disruption of Molecular Planarity and Symmetry
Minoru Ishikawa et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery
Stephan Meister et al.
SCIENCE (2011)
Improved Murine Model of Malaria Using Plasmodium falciparum Competent Strains and Non-Myelodepleted NOD-scid IL2Rγnull Mice Engrafted with Human Erythrocytes
Maria Belen Jimenez-Diaz et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Assessing the Bioisosterism of the Trifluoromethyl Group with a Protease Probe
Monika Jagodzinska et al.
CHEMMEDCHEM (2009)
Artemisinin Resistance in Plasmodium falciparum Malaria.
Arjen M. Dondorp et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Dissolution media simulating conditions in the proximal human gastrointestinal tract: An update
Ekarat Jantratid et al.
PHARMACEUTICAL RESEARCH (2008)
MMPs as therapeutic targets - Still a viable option?
Barbara Fingleton
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2008)
Fluorine in pharmaceuticals:: Looking beyond intuition
Klaus Mueller et al.
SCIENCE (2007)
In vitro and in vivo interaction of synthetic peroxide RBx11160 (OZ277) with piperaquine in Plasmodium models
Christopher Snyder et al.
EXPERIMENTAL PARASITOLOGY (2007)
Atropisomerism, biphenyls, and fluorine: A comparison of rotational barriers and twist angles
F Leroux
CHEMBIOCHEM (2004)
A high-throughput screening method for the determination of aqueous drug solubility using laser nephelometry in microtiter plates
CD Bevan et al.
ANALYTICAL CHEMISTRY (2000)