4.7 Article

Design, Synthesis, and Characterization of Novel sn-1 Heterocyclic DAG-Lactones as PKC Activators

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Diacylglycerol-evoked activation of PKC and PKD isoforms in regulation of glucose and lipid metabolism: a review

Katarzyna Kolczynska et al.

LIPIDS IN HEALTH AND DISEASE (2020)

Review Chemistry, Multidisciplinary

Prescribed drugs containing nitrogen heterocycles: an overview

Majid M. Heravi et al.

RSC ADVANCES (2020)

Review Chemistry, Multidisciplinary

Tetrazoles via Multicomponent Reactions

Constantinos G. Neochoritis et al.

CHEMICAL REVIEWS (2019)

Editorial Material Biochemistry & Molecular Biology

Heterocycles in Medicinal Chemistry

Josef Jampilek

MOLECULES (2019)

Article Biochemistry & Molecular Biology

Characterization of AJH-836, a diacylglycerol-lactone with selectivity for novel PKC isozymes

Mariana Cooke et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Article Biochemistry & Molecular Biology

COX-2 mediates pro-tumorigenic effects of PKCε in prostate cancer

Rachana Garg et al.

ONCOGENE (2018)

Review Cardiac & Cardiovascular Systems

Protein kinase C and cardiac dysfunction: a review

Raphael M. Singh et al.

HEART FAILURE REVIEWS (2017)

Article Biochemistry & Molecular Biology

Protein kinase C in cancer: The top five unanswered questions

Mariana Cooke et al.

MOLECULAR CARCINOGENESIS (2017)

Review Pharmacology & Pharmacy

The 1,2,3-triazole ring as a bioisostere in medicinal chemistry

Elisa Bonandi et al.

DRUG DISCOVERY TODAY (2017)

Article Biochemistry & Molecular Biology

Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP

Eleonora Elhalem et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2017)

Article Chemistry, Medicinal

Design and synthesis of protein kinase C epsilon selective diacylglycerol lactones (DAG-lactones)

Jihyae Ann et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)

Article Chemistry, Multidisciplinary

Versatile Enantioselective Synthesis of Functionalized Lactones via Copper-Catalyzed Radical Oxyfunctionalization of Alkenes

Rong Zhu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Article Chemistry, Organic

New click-chemistry methods for 1,2,3-triazoles synthesis: recent advances and applications

Jane Totobenazara et al.

TETRAHEDRON LETTERS (2015)

Article Biochemistry & Molecular Biology

Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP

Lia C. Garcia et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2014)

Review Chemistry, Multidisciplinary

C1 Domains: Structure and Ligand-Binding Properties

Joydip Das et al.

CHEMICAL REVIEWS (2014)

Article Chemistry, Multidisciplinary

A Novel Approach for the Synthesis of 5-Substituted-1H-tetrazoles

Batool Akhlaghinia et al.

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY (2012)

Review Biotechnology & Applied Microbiology

Protein kinase C, an elusive therapeutic target?

Daria Mochly-Rosen et al.

NATURE REVIEWS DRUG DISCOVERY (2012)

Review Chemistry, Multidisciplinary

Medicinal chemistry of tetrazoles

V. A. Ostrovskii et al.

RUSSIAN CHEMICAL BULLETIN (2012)

Article Chemistry, Medicinal

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

Nicholas A. Meanwell

JOURNAL OF MEDICINAL CHEMISTRY (2011)

Review Pharmacology & Pharmacy

Wealth of opportunity - The C1 domain as a target for drug development

P. M. Blumberg et al.

CURRENT DRUG TARGETS (2008)

Review Oncology

Protein kinase C and other diacylglycerol effectors in cancer

Erin M. Griner et al.

NATURE REVIEWS CANCER (2007)

Article Biochemistry & Molecular Biology

Improved protein-ligand docking using GOLD

ML Verdonk et al.

PROTEINS-STRUCTURE FUNCTION AND GENETICS (2003)

Review Chemistry, Multidisciplinary

Synthetic diacylglycerols (DAG) and DAG-lactones as activators of protein kinase C (PK-C)

VE Marquez et al.

ACCOUNTS OF CHEMICAL RESEARCH (2003)

Article Chemistry, Medicinal

Differential binding modes of diacylglycerol (DAG) and DAG lactones to protein kinase C (PK-C)

DM Sigano et al.

JOURNAL OF MEDICINAL CHEMISTRY (2003)