Preparation of MgO-MnO2 nanocomposite particles for cholesterol sensors

Various nanoparticles have been developed for bio-applications. However, nanocomposites particles, (NCPs) with effective and ability to sensing cholesterol, are still needed. Herein, we present new cholesterol and pH-responsive NCPs as sensor particles to promote sensitivity. The traditional method of mixing and grinding was used to fabricate the oxides of magnesium and manganese MgO-MnO2 NCPs with different mixing ratios. Structural properties, detection of cholesterol, and pH sensitivity were examined. Results propped the high efficiency of MgO-MnO2 NCPs compared with individual oxides (MgO and MnO2), low response time, while the analytical results confirmed the homogeneous structure of MgO-MnO2 NCPs. Particle size distribution results for NCPs were within 16.4 to 100 nm, which makes it promising in medical and bio-applications.

Automated summary

The novel cholesterol and pH-responsive NCPs as sensor particles can enhance sensitivity, and their structural properties, cholesterol detection, and pH sensitivity were investigated. Compared with individual oxides, MgO-MnO2 NCPs showed higher efficiency and lower response time, with a homogeneous structure.