Seasonal Coronavirus Pneumonia After SARS-CoV-2 Infection and Vaccination: New Frenemies?

Article Medicine, Research & Experimental

Recent endemic coronavirus infection is associated with less-severe COVID-19

Manish Sagar et al.

Summary: The study suggests that individuals with prior endemic coronavirus infections were tested more frequently for respiratory infections, but had similar rates of acquiring SARS-CoV-2. Additionally, patients with previous endemic coronavirus infections experienced less severe cases of COVID-19.

JOURNAL OF CLINICAL INVESTIGATION (2021)

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Article Biochemistry & Molecular Biology

Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection

Elizabeth M. Anderson et al.

Summary: Our research indicates that most individuals had antibodies against other seasonal human coronaviruses before the COVID-19 pandemic. Around 20% of these individuals also had antibodies that cross-reacted with SARS-CoV-2, but these antibodies did not offer protection against SARS-CoV-2 infections or hospitalizations.

CELL (2021)

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Review Microbiology

Viral Respiratory Pathogens and Lung Injury

Nicola Clementi et al.

Summary: Respiratory viruses can lead to a range of clinical manifestations, and the delicate balance between protective and dysregulated immune responses is crucial. Understanding the mechanisms of viral damage is key to developing new immune-based antiviral strategies.

CLINICAL MICROBIOLOGY REVIEWS (2021)

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Article Infectious Diseases

SARS-CoV-2 infection and COVID-19 severity in individuals with prior seasonal coronavirus infection

Saurabh Gombar et al.

Summary: The study shows that individuals with a history of seasonal coronavirus infection have similar rates of SARS-CoV-2 infection and severity of COVID-19 compared to those without such a history, indicating that prior infection with seasonal coronaviruses does not confer immunity to subsequent infection with SARS-CoV-2.

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE (2021)

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Article Virology

Lack of antibodies against seasonal coronavirus OC43 nucleocapsid protein identifies patients at risk of critical COVID-19

Martin Dugas et al.

Summary: The study analyzed the importance of seroreactivity against seasonal human coronaviruses in COVID-19 patients and found that patients who were OC43 negative were more likely to develop critical illness. A risk stratification based on sex and OC43 serostatus proved to be useful in predicting critical disease progression.

JOURNAL OF CLINICAL VIROLOGY (2021)

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Review Immunology

Comparative review of respiratory diseases caused by coronaviruses and influenza A viruses during epidemic season

Chao Jiang et al.

MICROBES AND INFECTION (2020)

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Review Microbiology

Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies

Wen Shi Lee et al.

NATURE MICROBIOLOGY (2020)

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Seasonal Coronavirus Pneumonia After SARS-CoV-2 Infection and Vaccination: New Frenemies?

相关参考文献

Recent endemic coronavirus infection is associated with less-severe COVID-19

Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection

Viral Respiratory Pathogens and Lung Injury

SARS-CoV-2 infection and COVID-19 severity in individuals with prior seasonal coronavirus infection

Lack of antibodies against seasonal coronavirus OC43 nucleocapsid protein identifies patients at risk of critical COVID-19

Comparative review of respiratory diseases caused by coronaviruses and influenza A viruses during epidemic season

Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies

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