4.7 Article

Huoxin Pill inhibits isoproterenol-induced transdifferentiation and collagen synthesis in cardiac fibroblasts through the TGF-β/Smads pathway

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Huoxin Pill ((sic)) Attenuates Cardiac Fibrosis by Suppressing TGF-β1/Smad2/3 Pathway in Isoproterenol-Induced Heart Failure Rats

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Summary: Huoxin Pill treatment alleviated heart failure and cardiac fibrosis in isoproterenol-induced HF rats by improving cardiac function and reducing pathological changes, as well as decreasing heart weight index and collagen expression levels. Additionally, it suppressed the TGF-beta 1/Smad2/3 pathway activation in cardiac tissues of HF rats.

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