期刊
FOOD CONTROL
卷 66, 期 -, 页码 151-157出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.foodcont.2016.02.002
关键词
AFB(1); EBI; Degradation; UPLC-Q-TOF/MS; Ames test; Cytotoxicity
资金
- National Natural Science Foundation of China [31401525]
- China Postdoctoral Science Foundation [2015M571666]
- Shandong province Postdoctoral Science Foundation [145635]
The degradation study of aflatoxin B-1 (AFB(1)) in aqueous medium was performed under electron beam irradiation (EBI) at various AFB(1) initial concentrations. It has been proven that the degradation of AFB1 in the selected ranges of concentrations follows pseudo first-order reaction kinetics well (R-2 > 0.95). Five degradation products of AFB(1) in aqueous solution were identified by UPLC-Q-TOF/MS, and the possible degradation pathway was proposed. The Ames and cytotoxicity tests were employed to evaluate the toxicity of the AFB(1) degradation products in aqueous solution, and the results indicated that the mutagenicity and cytotoxicity of EBI treated samples decreased significantly compared with that of untreated samples, but were not completely disappeared. The study provided clues involving the application of EBI methods in AFB(1) decontamination. (C) 2016 Elsevier Ltd. All rights reserved.
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