期刊
JOURNAL OF DERMATOLOGY
卷 48, 期 10, 页码 1550-1556出版社
WILEY
DOI: 10.1111/1346-8138.16062
关键词
psoriasis; retinal detachment; retinal diseases; retinal vascular occlusion; retinopathy
类别
资金
- Ministry of Science and Technology, Taiwan [MOST 107-2314-B-075-032-MY3-2]
Patients with psoriasis have a significantly higher risk of developing retinal diseases, including retinal detachment, retinal vascular occlusion, and retinopathy, compared to controls. Further studies are needed to explore the underlying pathophysiology of the relationship between psoriasis and retinal diseases.
Psoriasis has been associated with the risk of several ocular complications; however, its relationship with retinal diseases remains unknown. This study aimed to investigate the risk of developing retinal diseases in patients with psoriasis. Study participants were recruited from the National Health Insurance Research Database in Taiwan. A total of 11 729 psoriasis patients and 117 290 matched controls were included, showing an incidence rate of 121.15 and 28.34 cases of retinal diseases per 100 000 person-years, respectively. Compared with controls, patients with psoriasis had an adjusted hazard ratio (aHR) of 3.40 (95% confidence interval [CI], 2.63-4.39) for retinal diseases after adjustment for potential confounders. Regarding the individual retinal disease, psoriasis patients had a significantly higher risk of developing retinal detachment (aHR, 5.07; 95% CI, 2.92-8.79), retinal vascular occlusion (aHR, 3.75; 95% CI 2.42-5.82), and retinopathy (aHR, 2.84; 95% CI, 1.99-4.05) than controls. In conclusion, patients with psoriasis had a significantly higher risk of retinal diseases than controls. Further studies are necessary to investigate the pathophysiology underlying the relationship between psoriasis and retinal diseases.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据