4.5 Article

Simultaneous determination of dacomitinib and its major metabolite, O-desmethyl dacomitinib in human plasma by LC-MS/MS and its application to clinical testing in patients with non-small cell lung cancer

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Analytical

To quantify the small-molecule kinase inhibitors ceritinib, dacomitinib, lorlatinib, and nintedanib in human plasma by liquid chromatography/triple-quadrupole mass spectrometry

G. D. Marijn Veerman et al.

Summary: This article describes the development and validation of a UPLC-MS/MS method for simultaneous analysis of small-molecule kinase inhibitors in human plasma, meeting FDA requirements and demonstrating clinical applicability in patients with lung cancer.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2021)

Review Pharmacology & Pharmacy

First-Line Immune-Checkpoint Inhibitors in Non-Small Cell Lung Cancer: Current Landscape and Future Progress

Zhangfeng Huang et al.

FRONTIERS IN PHARMACOLOGY (2020)

Article Chemistry, Analytical

Quantitative bioanalytical assay for the human epidermal growth factor receptor (HER) inhibitor dacomitinib in rat plasma by UPLC-MS/MS

Xiangjun Qiu et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2019)

Review Medicine, General & Internal

Lung cancer: current therapies and new targeted treatments

Fred R. Hirsch et al.

LANCET (2017)

Article Oncology

A phase I, open-label, mass balance study of [14C] dacomitinib (PF-00299804) in healthy male volunteers

Carlo L. Bello et al.

CANCER CHEMOTHERAPY AND PHARMACOLOGY (2013)