4.6 Article

Precursor ion approach for simultaneous determination of nonethoxylated and ethoxylated alkylsulfate surfactants

期刊

JOURNAL OF CHROMATOGRAPHY A
卷 1653, 期 -, 页码 -

出版社

ELSEVIER
DOI: 10.1016/j.chroma.2021.462421

关键词

-

资金

  1. Warsaw University of Technology, Poland

向作者/读者索取更多资源

The new method provides simultaneous determination of sodium lauryl sulfate and sodium laureth sulfate homologues with high specificity and extended applicability. It successfully validated manufacturers' claims through simplified molecular ion monitoring and the use of a semi-quantitative approach.
We present a new liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for simultaneous determination of sodium lauryl sulfate and sodium laureth sulfate homologues in the range of alkyl chain length C 12 -C 16 with 0-5 ethoxy groups. The method is based on scanning the precursor ions fragmenting to m/z 80 and 97 (Precursor Ion Scanning mode), which makes it specific for species with easily cleavable sulfate groups. By monitoring fragmentation of thus discovered quasi-molecular ions we were able to unequivocally identify all sulfate species present in complex mixtures of alkyl and alkyl-ether sulfates with molecular weight ranging from 200 to 600 m/z . Because of the intrinsic sulfate-sensitivity, the presented method can be also applied to non-sodium salts of alkyl- and alkyl-ether sulfates (e.g. ammonium, mono- or triethanolamine, etc.), which are often used by cosmetic manufacturers to justify the misleading SLS- and SLES-free claims (where SLS and SLES refer to sodium lauryl sulfate and sodium laureth sulfate, respectively). The use of reversed phase liquid chromatography (RPLC) column with C4 instead of C18 shortened significantly the overall analysis time and allowed us to use a semiquantitative method (based on single standard for Quantitative Analysis of Multi-component System, QAMS) to determine several SLS and SLES homologues in one run with the limit of quantification (LOQ) = 0.4 mu g/mL and of detection (LOD) in the range 0.12-0.97 mu g/mL. The method was successfully applied to 17 commercially available cosmetic/household products allowing verification of their manufacturers' declarations. (c) 2021 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license ( http://creativecommons.org/licenses/by/4.0/ )

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据